Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL28077889

CC(C)(C)C(C)(C(=O)O)c1ccc(O)cc1.S

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.48
ESR2 Q92731 10/20 0.48
ESRRG P62508 4/20 0.48
CYP3A4 P08684 3/20 0.48
TYR P14679 2/20 0.48
LMNA P02545 1/20 0.48
AR P10275 1/20 0.48
HPGD P15428 1/20 0.48
TSHR P16473 1/20 0.48
SLC6A2 P23975 1/20 0.48
SLC6A4 P31645 1/20 0.48
HTR6 P50406 1/20 0.48
SLC6A3 Q01959 1/20 0.48
HSD17B10 Q99714 1/20 0.48
ALDH1A1 P00352 2/20 0.47
BLM P54132 1/20 0.43
SHBG P04278 1/20 0.41
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7044103 0.98 ESR1 (0.50) ESR1ESR2ESRRGCYP3A4TYR
SCHEMBL28386593 0.83 ESR1 (0.38) ESR1ESR2ESRRGCYP3A4TYR
SCHEMBL28786874 0.81 LMNA (0.40) ESR1ESR2ESRRGCYP3A4TYR
SCHEMBL3726386 0.80 CYP1A2 (0.54) ESR1ESR2CYP3A4TSHRALDH1A1
SCHEMBL19723163 0.80 HSD17B10 (0.47) ESR1ESR2ESRRGCYP3A4TYR
SCHEMBL28390791 0.79 ESR1 (0.48) ESR1ESR2ESRRGCYP3A4TYR
SCHEMBL7037031 0.79 MEN1 (0.46) HPGD
SCHEMBL6349689 0.79 KMT2A (0.50) CYP3A4TSHR
SCHEMBL28652506 0.79 ESR1 (0.48) ESR1ESR2ESRRGCYP3A4TYR
SCHEMBL28938751 0.78 CYP1A2 (0.52) ESR1ESR2CYP3A4TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106279920-A A kind of crosslinkable polyethylene Insulation Material of the low by-product of 220kV and preparation method thereof 安徽滁州德威新材料有限公司 2017-01-04 CN claimed
CN-106221594-A A kind of heat discoloration photovoltaic module 中天光伏材料有限公司 2016-12-14 CN claimed
CN-105856762-A Solar battery backboard and production technology thereof 中天光伏材料有限公司 2016-08-17 CN claimed
CN-106279920-A A kind of crosslinkable polyethylene Insulation Material of the low by-product of 220kV and preparation method thereof 安徽滁州德威新材料有限公司 2017-01-04 CN disclosed
CN-105856762-A Solar battery backboard and production technology thereof 中天光伏材料有限公司 2016-08-17 CN disclosed