(Chloromethyl)Benzene

(Chloromethyl)Benzene

SCHEMBL28077974

ClCc1ccccc1.O=C(O)c1cc[nH]n1

nearest known ligand 0.47

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.47
P4HTM Q9NXG6 2/20 0.40
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.36
ASPH Q12797 1/20 0.36
RIOX2 Q8IUF8 1/20 0.36
KDM8 Q8N371 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A3 Q01959 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 1/20 0.35
NAPRT Q6XQN6 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PAM P19021 1/20 0.35
MMP2 P08253 1/20 0.35
MMP9 P14780 1/20 0.35
MMP12 P39900 1/20 0.35
HCAR3 P49019 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL15668588 0.84 ALOX15 (0.46) HCAR2P4HTMALDH1A1KDM4EKMT2A
SCHEMBL7790 0.82
Biphenyl SCHEMBL27870431 0.80 LMNA (0.43) HCAR2P4HTMALDH1A1KDM4ETDP1
Phosphine SCHEMBL28881621 0.80 KDM4E (0.41) HCAR2P4HTMALDH1A1KDM4EASPH
Bromide SCHEMBL6269164 0.80
Ammonia Solution, Strong SCHEMBL20400056 0.80
SCHEMBL28930585 0.80
SCHEMBL21837234 0.80 KDM4E (0.41) HCAR2P4HTMALDH1A1KDM4EASPH
Hydrochloric Acid SCHEMBL1662114 0.80
SCHEMBL28067891 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105777717-A Pyrazolyl pyrimidinyl ether compound and use thereof 沈阳中化农药化工研发有限公司 2016-07-20 CN disclosed