Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 3/20 | 0.45 |
| ▸ | CDC25B | P30305 | 3/20 | 0.45 |
| ▸ | TDP2 | O95551 | 2/20 | 0.45 |
| ▸ | NSD2 | O96028 | 2/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.41 |
| ▸ | PADI1 | Q9ULC6 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10434480 | 0.88 | TDP2 (0.49) | S100A4CDC25BTDP2NSD2PAX8 | |
| SCHEMBL30737515 | 0.79 | CDC25B (0.31) | S100A4CDC25BTDP2NSD2PAX8 | |
| SCHEMBL28371493 | 0.74 | PIM1 (0.43) | S100A4CDC25BTDP2NSD2PAX8 | |
| SCHEMBL21815564 | 0.71 | S100A4 (0.52) | S100A4CDC25BTDP2NSD2PAX8 | |
| SCHEMBL2917444 | 0.71 | S100A4 (0.52) | S100A4CDC25BTDP2NSD2PAX8 | |
| SCHEMBL29498808 | 0.69 | TDP2 (0.41) | S100A4CDC25BTDP2NSD2PAX8 | |
| SCHEMBL618332 | 0.69 | TDP2 (0.41) | S100A4CDC25BTDP2NSD2PAX8 | |
| Hydrochloric Acid SCHEMBL15327096 | 0.68 | TDP2 (0.39) | S100A4CDC25BTDP2NSD2PAX8 | |
| SCHEMBL26512083 | 0.67 | TDP2 (0.38) | S100A4CDC25BTDP2NSD2PAX8 | |
| SCHEMBL9384246 | 0.67 | TDP2 (0.42) | S100A4CDC25BTDP2NSD2PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057061-A | USP7 inhibitors | 首药控股(北京)股份有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-115298192-A | 4' -O-methylene phosphonate nucleic acids and analogs thereof | 迪克纳制药公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-105777747-A | 4-chloro-7-azaindole and preparation method thereof | 叶芳 | 2016-07-20 | — | — | CN | disclosed |