Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28078042 | 0.84 | ALDH1A1 (0.59) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3802062 | 0.83 | MAPT (0.65) | PRKDCMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL2027015 | 0.83 | MAPT (0.65) | PRKDCMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL2028974 | 0.80 | MAPT (0.57) | PRKDCMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL2028976 | 0.80 | MAPT (0.57) | PRKDCMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11487173 | 0.77 | GSK3B (0.54) | PRKDCMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11487174 | 0.77 | GSK3B (0.54) | PRKDCMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL334850 | 0.77 | MAPT (0.74) | PRKDCMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL18694390 | 0.76 | MEN1 (0.52) | PRKDCMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL18694393 | 0.76 | MEN1 (0.52) | PRKDCMAPTALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103635470-B | Chromene compounds and solidification compound | 株式会社德山 | 2016-12-21 | — | — | CN | disclosed |
| CN-103517899-B | Chromene compounds | 株式会社德山 | 2016-06-15 | — | — | CN | disclosed |