Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.58 |
| ▸ | CTSS | P25774 | 3/20 | 0.58 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3730085 | 0.88 | CTSK (0.58) | CTSKCTSSPSENENCA2CA1 | |
| SCHEMBL3730087 | 0.88 | CTSK (0.58) | CTSKCTSSPSENENCA2CA1 | |
| SCHEMBL9743636 | 0.87 | CTSK (0.61) | CTSKCTSSPSENENCA2CA1 | |
| SCHEMBL1486221 | 0.87 | PSENEN (0.62) | CTSKCTSSPSENENCA2CA1 | |
| SCHEMBL1486223 | 0.87 | PSENEN (0.62) | CTSKCTSSPSENENCA2CA1 | |
| SCHEMBL245495 | 0.87 | PSENEN (0.62) | CTSKCTSSPSENENCA2CA1 | |
| SCHEMBL8466502 | 0.86 | CTSS (0.59) | CTSKCTSSPSENENCA2CA1 | |
| SCHEMBL8466501 | 0.86 | CTSS (0.59) | CTSKCTSSPSENENCA2CA1 | |
| SCHEMBL28469162 | 0.84 | CTSK (0.58) | CTSKCTSSPSENENCA2CA1 | |
| SCHEMBL15488335 | 0.83 | CTSK (0.57) | CTSKCTSSPSENENCA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105764904-A | Aza-pyridone compounds and uses thereof | 艾丽奥斯生物制药有限公司 | 2016-07-13 | — | — | CN | disclosed |