Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28220405 | 0.81 | ALDH1A1 (0.50) | MAPTALDH1A1HTTHSP90AA1PDK1 | |
| SCHEMBL15442018 | 0.81 | ALDH1A1 (0.48) | MAPTALDH1A1SMN1; SMN2NPC1TP53 | |
| SCHEMBL2537515 | 0.81 | ALDH1A1 (0.71) | MAPTALDH1A1HTTHSP90AA1PDK1 | |
| SCHEMBL28148839 | 0.80 | HSD17B2 (0.56) | MTNR1AMTNR1B | |
| SCHEMBL28865681 | 0.80 | EPHX2 (0.42) | MAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL24106352 | 0.79 | ALDH1A1 (0.50) | MAPTALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL7823913 | 0.79 | ALDH1A1 (0.55) | MAPTALDH1A1HTTHSP90AA1PDK1 | |
| SCHEMBL4889215 | 0.79 | APP (0.38) | MAPTALDH1A1HSP90AA1PDK1PDK2 | |
| SCHEMBL12534115 | 0.79 | HSP90AA1 (0.58) | MAPTALDH1A1HTTHSP90AA1PDK1 | |
| SCHEMBL28948525 | 0.78 | TRPM8 (0.52) | MAPTNPC1RAB9AKMT2ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119372671-A | Method for synthesizing amino acid compound by participation of carbon dioxide | 新疆大学 | 2025-01-28 | — | — | CN | disclosed |
| CN-118978472-A | Preparation method of indolone compound connected with gamma-ketosulfone structure | 安阳师范学院 | 2024-11-19 | — | — | CN | disclosed |
| CN-118255706-A | Synthesis method of oxindole compound | 浙江工业大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-115094449-B | Method for synthesizing and marking halogenated indolone by using freon-type methane as carbon-synthesis son and application thereof | 上海交通大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-113773277-B | Synthesis method of 4H-1,2, 4-benzothiadiazine-1, 1-dioxide derivative | 兰州大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-115094449-A | Method for synthesizing and marking halogenated indolone by using freon type methane as carbon-carbon synthesizer and application thereof | 上海交通大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-113214273-B | Synthesis method of tetrahydrofuran indole compound | 台州学院 | 2022-06-17 | — | — | CN | disclosed |
| CN-113214273-A | Synthesis method of tetrahydrofuran indole compound | 台州学院 | 2021-08-06 | — | — | CN | disclosed |
| CN-106749214-B | Compound containing 1, 3-benzoxazole difluoromethylene indolone and preparation method thereof | 上海大学 | 2020-01-17 | — | — | CN | disclosed |
| CN-108752258-A | Nickel is catalyzed Synthesis of Indole ketones derivant | 南开大学 | 2018-11-06 | — | — | CN | disclosed |
| CN-106048648-B | The electrochemical catalysis synthetic method of the oxindole class compound of 3- sulfonic groups substitution | 北京工业大学 | 2018-05-25 | — | — | CN | disclosed |
| CN-106048648-A | Electrochemical catalysis synthesis method of 3-sulfonyl substituted oxo indoles compound | 北京工业大学 | 2016-10-26 | — | — | CN | disclosed |