Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | YTHDF3 | Q7Z739 | 1/20 | 0.35 |
| ▸ | YTHDF1 | Q9BYJ9 | 1/20 | 0.35 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11841644 | 0.85 | CYP1A2 (0.71) | CYP1A2LMNAALDH1A1GPR84MEN1 | |
| SCHEMBL27735725 | 0.83 | CYP1A2 (0.69) | CYP1A2LMNAALDH1A1GPR84MEN1 | |
| Ammonia Solution, Strong SCHEMBL28111982 | 0.83 | CYP1A2 (0.69) | CYP1A2LMNAALDH1A1GPR84MEN1 | |
| SCHEMBL1050338 | 0.82 | CYP1A2 (0.67) | CYP1A2LMNAALDH1A1GPR84MEN1 | |
| SCHEMBL29216003 | 0.82 | CYP1A2 (0.67) | CYP1A2LMNAALDH1A1GPR84MEN1 | |
| SCHEMBL118496 | 0.82 | CYP1A2 (1.00) | CYP1A2LMNAALDH1A1GPR84MEN1 | |
| SCHEMBL2269068 | 0.79 | CYP1A2 (0.62) | CYP1A2LMNAALDH1A1GPR84MEN1 | |
| SCHEMBL11042365 | 0.79 | CYP1A2 (0.68) | CYP1A2LMNAALDH1A1GPR84MEN1 | |
| SCHEMBL2516165 | 0.79 | CYP1A2 (0.62) | CYP1A2LMNAALDH1A1GPR84MEN1 | |
| SCHEMBL917082 | 0.77 | GPR84 (0.68) | CYP1A2LMNAALDH1A1GPR84MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105861339-B | Recombination Mortierella alpina, its construction method and the application of one plant of overexpression GTP cyclohydrolase gene | 江南大学 | 2019-10-18 | — | — | CN | disclosed |
| CN-104004760-B | A kind of expression equipment and its aspergillus oryzae genetic engineering bacterium being used in Aspergillus oryzae cell secreting, expressing foreign protein | 华东理工大学 | 2017-11-28 | — | — | CN | disclosed |
| CN-106456769-A | Enhanced production of recombinant CRM197 in e. coli | 斯卡拉布基因组有限责任公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-105861339-A | Recombination mortierella alpine of overexpression GTP ring type hydrolytic enzyme gene and construction method and application of recombination mortierella alpine | 江南大学 | 2016-08-17 | — | — | CN | disclosed |