Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4283121 | 0.82 | CYP1A2 (0.64) | CYP1A2LMNAALDH1A1GPR84MEN1 | |
| SCHEMBL28584034 | 0.82 | CYP1A2 (0.58) | CYP1A2LMNAALDH1A1GPR84MEN1 | |
| SCHEMBL118496 | 0.81 | CYP1A2 (1.00) | CYP1A2LMNAALDH1A1GPR84MEN1 | |
| SCHEMBL11957579 | 0.78 | LMNA (0.65) | CYP1A2LMNAALDH1A1GPR84MEN1 | |
| SCHEMBL1050338 | 0.77 | CYP1A2 (0.67) | CYP1A2LMNAALDH1A1GPR84MEN1 | |
| SCHEMBL29216003 | 0.77 | CYP1A2 (0.67) | CYP1A2LMNAALDH1A1GPR84MEN1 | |
| SCHEMBL917082 | 0.76 | GPR84 (0.68) | CYP1A2LMNAALDH1A1GPR84MEN1 | |
| SCHEMBL11884800 | 0.76 | CYP1A2 (0.56) | CYP1A2LMNAALDH1A1GPR84MEN1 | |
| Orotic Acid SCHEMBL18894201 | 0.75 | ALDH1A1 (0.88) | CYP1A2LMNAALDH1A1GPR84MEN1 | |
| SCHEMBL2516165 | 0.74 | CYP1A2 (0.62) | CYP1A2LMNAALDH1A1GPR84MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119995-A1 | NEW ACYLATED DERIVATIVES OF DEHYDRO OROTIC ACID, PREPARATIONS THEREOF AND UTILIZATIONS THEREOF AS DRUG | CORBIERE, Jérôme (FR) | 1984-10-03 | — | — | EP | disclosed |
| WO-1984001385-A1 | NEW ACYLATED DERIVATIVES OF DEHYDRO OROTIC ACID, PREPARATIONS THEREOF AND UTILIZATIONS THEREOF AS DRUG | CORBIERE JEROME | 1984-04-12 | — | — | WO | disclosed |