Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.78 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.78 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29405385 | 0.88 | GABRA1 (1.00) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL8081993 | 0.88 | GABRA1 (0.64) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL8081975 | 0.88 | GABRA1 (0.64) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL8075582 | 0.87 | GABRA1 (0.72) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL8077322 | 0.87 | GABRA1 (0.72) | GABRA1GABRB1CA1CA2GAA | |
| SCHEMBL2410206 | 0.85 | GABRA1 (0.70) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL8077435 | 0.85 | GABRA1 (0.60) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL2416215 | 0.85 | GABRA1 (0.70) | GABRA1GABRB1CA1CA2GAA | |
| SCHEMBL2417465 | 0.85 | GABRA1 (0.70) | GABRA1GABRB1CA1CA2GAA | |
| SCHEMBL8075584 | 0.85 | GABRA1 (0.70) | GABRA1GABRB1CA1CA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105849088-A | Pharmacologically active compounds | 利物浦大学 | 2016-08-10 | — | — | CN | claimed |
| CN-114149311-A | Method for preparing 4-hydroxybenzophenone compound by taking p-methylenequinone as substrate | 上海应用技术大学 | 2022-03-08 | — | — | CN | disclosed |
| CN-105849088-A | Pharmacologically active compounds | 利物浦大学 | 2016-08-10 | — | — | CN | disclosed |