Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.72 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28078271 | 0.87 | GABRA1 (0.78) | GABRA1GABRB1GAAHTTLMNA | |
| SCHEMBL8075582 | 0.86 | GABRA1 (0.72) | GABRA1GABRB1GAAHTTLMNA | |
| SCHEMBL2410206 | 0.84 | GABRA1 (0.70) | GABRA1GABRB1GAAHTTLMNA | |
| SCHEMBL8075584 | 0.84 | GABRA1 (0.70) | GABRA1GABRB1GAAHTTLMNA | |
| SCHEMBL2417465 | 0.84 | GABRA1 (0.70) | GABRA1GABRB1GAAHTTLMNA | |
| SCHEMBL2416215 | 0.84 | GABRA1 (0.70) | GABRA1GABRB1GAAHTTLMNA | |
| SCHEMBL2413335 | 0.84 | GABRA1 (0.70) | GABRA1GABRB1GAAHTTLMNA | |
| SCHEMBL29405385 | 0.84 | GABRA1 (1.00) | GABRA1GABRB1GAAHTTLMNA | |
| SCHEMBL8077372 | 0.81 | GABRA1 (0.66) | GABRA1GABRB1GAAHTTLMNA | |
| SCHEMBL8067655 | 0.81 | GABRA1 (0.81) | GABRA1GABRB1GAAHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149311-A | Method for preparing 4-hydroxybenzophenone compound by taking p-methylenequinone as substrate | 上海应用技术大学 | 2022-03-08 | — | — | CN | disclosed |
| EP-2520290-A1 | Propofol analogs, process for their preparation, and methods of use | Abraxis BioScience, LLC (US) | 2012-11-07 | — | — | EP | disclosed |
| US-7825182-B2 | Nanocomposite comprising stabilization functionalized thermoplastic polyolefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-11-02 | — | — | US | disclosed |
| US-7825182-B2 | Nanocomposite comprising stabilization functionalized thermoplastic polyolefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-11-02 | — | — | US | disclosed |
| US-7586008-B2 | Propofol analogs, process for their preparation, and methods of use | ABRAXIS BIOSCIENCE, INC. (US) | 2009-09-08 | — | — | US | disclosed |
| US-7586008-B2 | Propofol analogs, process for their preparation, and methods of use | ABRAXIS BIOSCIENCE, INC. (US) | 2009-09-08 | — | — | US | disclosed |
| US-20080275100-A1 | PROPOFOL ANALOGS, PROCESS FOR THEIR PREPARATION, AND METHODS OF USE | ABRAXIS BIOSCIENCE, INC. (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080275100-A1 | PROPOFOL ANALOGS, PROCESS FOR THEIR PREPARATION, AND METHODS OF USE | ABRAXIS BIOSCIENCE, INC. (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080214707-A1 | Nanocomposite Comprising Stabilization Functionalized Thermoplastic Polyolefins | EXXONMOBIL CHEMICAL PATENTS INC. | 2008-09-04 | — | — | US | disclosed |
| US-20080214707-A1 | Nanocomposite Comprising Stabilization Functionalized Thermoplastic Polyolefins | EXXONMOBIL CHEMICAL PATENTS INC. | 2008-09-04 | — | — | US | disclosed |
| US-7371793-B2 | Nanocomposite comprising stabilization functionalized thermoplastic polyolefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-05-13 | — | — | US | disclosed |
| US-7371793-B2 | Nanocomposite comprising stabilization functionalized thermoplastic polyolefins | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-05-13 | — | — | US | disclosed |
| US-20070185217-A1 | Propofol analogs, process for their preparation, and methods of use | ABRAXIS BIOSCIENCE, INC. (US) | 2007-08-09 | — | — | US | disclosed |
| US-20070185217-A1 | Propofol analogs, process for their preparation, and methods of use | ABRAXIS BIOSCIENCE, INC. (US) | 2007-08-09 | — | — | US | disclosed |
| WO-2005063665-A1 | PROPOFOL ANALOGS, PROCESS FOR THEIR PREPARATION, AND METHODS OF USE | ABRAXIS BIOSCIENCE, INC (US) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275100-A1 | PROPOFOL ANALOGS, PROCESS FOR THEIR PREPARATION, AND METHODS OF USE | CYP3A5, CYP3A4, GABARAP | GABRA1 32/4885GABRB1 81/4885GAA 3632/4885 |
| US-20070185217-A1 | Propofol analogs, process for their preparation, and methods of use | CYP3A5, CYP3A4, GABARAP | GABRA1 32/4885GABRB1 81/4885GAA 3632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.