Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7509648 | 0.86 | CYP19A1 (0.54) | MAPTNPC1LMNAMEN1POLB | |
| SCHEMBL8816050 | 0.80 | MAPT (0.54) | MAPTNPC1LMNAMEN1POLB | |
| SCHEMBL6738366 | 0.79 | TSHR (0.76) | MAPTNPC1LMNAMEN1POLB | |
| SCHEMBL7509794 | 0.79 | ALDH1A1 (0.46) | MAPTNPC1LMNAMEN1POLB | |
| SCHEMBL11392466 | 0.77 | TSHR (0.73) | MAPTNPC1LMNAMEN1POLB | |
| SCHEMBL11392461 | 0.77 | TSHR (0.73) | MAPTNPC1LMNAMEN1POLB | |
| Iodide SCHEMBL30804629 | 0.77 | TSHR (0.73) | MAPTNPC1LMNAMEN1POLB | |
| Iodide SCHEMBL28598177 | 0.77 | TSHR (0.73) | MAPTNPC1LMNAMEN1POLB | |
| SCHEMBL28471286 | 0.77 | TSHR (0.73) | MAPTNPC1LMNAMEN1POLB | |
| SCHEMBL20510943 | 0.77 | CNR1 (0.47) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106414433-A | Diazaspiroalkaneone-substituted oxazole derivatives as spleen tyrosine kinase inhibitors | AB科学有限公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-103717591-B | Oxazole and Thiazole Derivatives as Selective Protein Kinase (C-KIT) Inhibitors | AB科学有限公司 | 2016-08-24 | — | — | CN | disclosed |