Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28078880 | 1.00 | POLB (0.42) | POLBCHRM3SCN9AL3MBTL1CACNA1I | |
| SCHEMBL17061729 | 0.88 | POLB (0.39) | POLBCHRM3SCN9AL3MBTL1NOTUM | |
| SCHEMBL28078708 | 0.87 | CHRM3 (0.41) | POLBCHRM3SCN9ACACNA1IKCNH2 | |
| SCHEMBL28078905 | 0.86 | ACLY (0.39) | POLBCHRM3CACNA1IKCNH2STS | |
| SCHEMBL28277464 | 0.81 | KMT2A (0.38) | CHEK2 | |
| SCHEMBL17061848 | 0.78 | CHEK2 (0.51) | POLBSTSCHEK2 | |
| SCHEMBL16770949 | 0.78 | CHEK2 (0.51) | POLBSTSCHEK2 | |
| SCHEMBL16771007 | 0.78 | CHEK2 (0.51) | POLBSTSCHEK2 | |
| SCHEMBL27874081 | 0.76 | CHRM3 (0.49) | CHRM3 | |
| SCHEMBL27721841 | 0.76 | CHRM3 (0.49) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793238-A | Substituted benzamides and methods of use thereof | 基因泰克公司 | 2016-07-20 | — | — | CN | disclosed |