Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28237166 | 0.94 | EPHX2 (0.42) | EPHX2ACACBSCN1ASCN2ASCN3A | |
| SCHEMBL28328550 | 0.85 | EPHX2 (0.46) | KMT2AEPHX2SCN1ASCN2ASCN3A | |
| SCHEMBL27874081 | 0.82 | CHRM3 (0.49) | ALDH1A1EPHX2ACACBFFAR4 | |
| SCHEMBL27911300 | 0.82 | CHRM3 (0.49) | ALDH1A1EPHX2ACACBFFAR4 | |
| SCHEMBL27721841 | 0.82 | CHRM3 (0.49) | ALDH1A1EPHX2ACACBFFAR4 | |
| SCHEMBL28078956 | 0.81 | POLB (0.42) | CHEK2 | |
| SCHEMBL28078880 | 0.81 | POLB (0.42) | CHEK2 | |
| SCHEMBL28555962 | 0.81 | CYP2D6 (0.49) | ALDH1A1 | |
| SCHEMBL27833492 | 0.80 | ALDH1A1 (0.48) | KMT2AALDH1A1SMN1; SMN2HCRTR1HCRTR2 | |
| SCHEMBL28095478 | 0.80 | ALDH1A1 (0.48) | KMT2AALDH1A1SMN1; SMN2HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109310671-A | BRUTON'S TYROSINE KINASE INHIBITORS | 淄博百极常生制药有限公司 | 2019-02-05 | — | — | CN | disclosed |