Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.68 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.68 |
| ▸ | HTR2A | P28223 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | HTR6 | P50406 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | NQO2 | P16083 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12352511 | 0.87 | HTR2A (0.79) | MTNR1AMTNR1BHTR2AMEN1KMT2A | |
| SCHEMBL3816723 | 0.84 | HTR2A (0.73) | MTNR1AMTNR1BHTR2AMEN1KMT2A | |
| SCHEMBL13715395 | 0.82 | HTR2A (0.75) | MTNR1AMTNR1BHTR2AMEN1KMT2A | |
| SCHEMBL9531245 | 0.81 | MTNR1A (0.62) | MTNR1AMTNR1BHTR2AMEN1KMT2A | |
| SCHEMBL30630306 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1BMEN1KMT2AMAPT | |
| SCHEMBL4490583 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1BMEN1KMT2AMAPT | |
| SCHEMBL29874859 | 0.81 | HTR2A (1.00) | MTNR1AMTNR1BHTR2AMEN1KMT2A | |
| SCHEMBL379337 | 0.81 | HTR2A (1.00) | MTNR1AMTNR1BHTR2AMEN1KMT2A | |
| SCHEMBL29899096 | 0.81 | CYP2D6 (0.78) | MTNR1AMTNR1BHTR2AMEN1KMT2A | |
| SCHEMBL3812224 | 0.81 | CYP2D6 (0.78) | MTNR1AMTNR1BHTR2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669525-B | A kind of synthetic method of N ((2 (base of 1,3 dioxoisoindolin 2) propiono) 5 methoxyl groups) formamide | 苏州艾缇克药物化学有限公司 | 2018-03-09 | — | — | CN | disclosed |
| CN-105669525-A | Synthetic method of N-((2-(1,3-dioxo-dihydroisoindol-2-yl)-propionyl)-5-methoxy)formamide | 苏州艾缇克药物化学有限公司 | 2016-06-15 | — | — | CN | disclosed |