SCHEMBL28079117

SCHEMBL28079117

CCCCCCCC[Si](C)(OCCC)OCCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.38
TSHR P16473 1/20 0.38
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
USP2 O75604 1/20 0.32
HTT P42858 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPT P10636 1/20 0.32
LMNA P02545 1/20 0.31
LPAR3 Q9UBY5 5/20 0.31
CA1 P00915 5/20 0.31
CA2 P00918 5/20 0.31
CA9 Q16790 5/20 0.31
LPAR2 Q9HBW0 4/20 0.31
LPAR1 Q92633 2/20 0.31
NAAA Q02083 1/20 0.31
CA12 O43570 1/20 0.31
CA3 P07451 1/20 0.31
CA4 P22748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29126578 1.00 THRB (0.38) THRBTSHRALDH1A1TDP1USP2
SCHEMBL5572069 1.00 THRB (0.38) THRBTSHRALDH1A1TDP1USP2
SCHEMBL27922600 1.00 THRB (0.38) THRBTSHRALDH1A1TDP1USP2
SCHEMBL28078990 1.00 THRB (0.38) THRBTSHRALDH1A1TDP1USP2
SCHEMBL5570797 1.00 THRB (0.38) THRBTSHRALDH1A1TDP1USP2
SCHEMBL27581119 1.00 THRB (0.38) THRBTSHRALDH1A1TDP1USP2
SCHEMBL8092138 0.98 THRB (0.36) THRBTSHRALDH1A1TDP1USP2
SCHEMBL28078992 0.98 TSHR (0.33) THRBTSHR
SCHEMBL707266 0.93
SCHEMBL11332073 0.91 THRB (0.38) THRBTSHRALDH1A1TDP1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240270908-A1 POLYSILSESQUIOXANE COMPOSITION AND CURED PRODUCT NIPPON SHOKUBAI CO., LTD. (JP) 2024-08-15 US disclosed
CN-117043276-A Polysilsesquioxane composition and cured product 株式会社日本触媒 2023-11-10 CN disclosed
WO-2022202800-A1 POLYSILSESQUIOXANE COMPOSITION AND CURED PRODUCT 株式会社日本触媒 2022-09-29 WO disclosed
CN-106062044-B Polysiloxane copolymer, and antistatic agent and resin composition containing same 信越化学工业株式会社 2019-11-26 CN disclosed
CN-105916913-B Polysiloxane copolymer and antistatic agent containing it 广荣化学工业株式会社 2019-10-25 CN disclosed
CN-105324407-B Active energy ray-curable composition 株式会社钟化 2017-07-28 CN disclosed
CN-106062044-A Polysiloxane copolymer, and antistatic agent and resin composition containing same 信越化学工业株式会社 2016-10-26 CN disclosed
CN-105916913-A Polysiloxane copolymer and antistatic agent comprising same 广荣化学工业株式会社 2016-08-31 CN disclosed