SCHEMBL28078992

SCHEMBL28078992

CCCCC[Si](C)(OCCC)OCCC

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
THRB P10828 1/20 0.33
ADRB2 P07550 1/20 0.31
ADRB1 P08588 1/20 0.31
ADRB3 P13945 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27922600 0.98 THRB (0.38) TSHRTHRB
SCHEMBL5572069 0.98 THRB (0.38) TSHRTHRB
SCHEMBL28079117 0.98 THRB (0.38) TSHRTHRB
SCHEMBL28078990 0.98 THRB (0.38) TSHRTHRB
SCHEMBL5570797 0.98 THRB (0.38) TSHRTHRB
SCHEMBL29126578 0.98 THRB (0.38) TSHRTHRB
SCHEMBL27581119 0.98 THRB (0.38) TSHRTHRB
SCHEMBL8092138 0.95 THRB (0.36) TSHRTHRB
SCHEMBL707266 0.95
SCHEMBL1609048 0.92 ADRB2 (0.32) TSHRADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240270908-A1 POLYSILSESQUIOXANE COMPOSITION AND CURED PRODUCT NIPPON SHOKUBAI CO., LTD. (JP) 2024-08-15 US disclosed
CN-117043276-A Polysilsesquioxane composition and cured product 株式会社日本触媒 2023-11-10 CN disclosed
WO-2022202800-A1 POLYSILSESQUIOXANE COMPOSITION AND CURED PRODUCT 株式会社日本触媒 2022-09-29 WO disclosed
CN-106062044-B Polysiloxane copolymer, and antistatic agent and resin composition containing same 信越化学工业株式会社 2019-11-26 CN disclosed
CN-105916913-B Polysiloxane copolymer and antistatic agent containing it 广荣化学工业株式会社 2019-10-25 CN disclosed
CN-106062044-A Polysiloxane copolymer, and antistatic agent and resin composition containing same 信越化学工业株式会社 2016-10-26 CN disclosed
CN-105916913-A Polysiloxane copolymer and antistatic agent comprising same 广荣化学工业株式会社 2016-08-31 CN disclosed