Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMAD3 | P84022 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2951373 | 0.83 | MMP13 (0.60) | KDM4EHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL2950369 | 0.78 | HRH3 (0.53) | SMAD3KDM4EHPGDHSD17B10F7 | |
| SCHEMBL2949966 | 0.76 | HRH3 (0.51) | SMAD3KDM4EHPGDHSD17B10F7 | |
| SCHEMBL2952598 | 0.76 | HRH3 (0.53) | SMAD3KDM4EHPGDHSD17B10F7 | |
| SCHEMBL2950114 | 0.76 | HRH3 (0.73) | SMAD3PIN1ALDH1A1HRH3KMT2A | |
| SCHEMBL2943625 | 0.76 | HRH3 (0.53) | SMAD3KDM4EPIN1HRH3KMT2A | |
| SCHEMBL2949495 | 0.75 | HRH3 (0.50) | SMAD3KDM4EHPGDHSD17B10F7 | |
| SCHEMBL15642795 | 0.75 | SMAD3 (0.50) | SMAD3KDM4EHPGDHSD17B10F7 | |
| SCHEMBL2951314 | 0.75 | HRH3 (0.64) | SMAD3KDM4EHPGDHSD17B10F7 | |
| SCHEMBL8197851 | 0.72 | SMAD3 (0.60) | SMAD3KDM4EHPGDHSD17B10F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658625-A | Indole amide compound as inhibitor of necrosis | 株式会社LG生命科学 | 2016-06-08 | — | — | CN | disclosed |