Chlorobenzene

Chlorobenzene

SCHEMBL28079345

C=CC(=O)OC(C)(C)C.Clc1ccccc1

nearest known ligand 0.41

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XPO1 O14980 1/20 0.40
THRB P10828 1/20 0.39
PPARA Q07869 3/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2C19 P33261 2/20 0.39
MAPT P10636 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
TSHR P16473 2/20 0.38
PPARG P37231 1/20 0.38
ALDH1A1 P00352 2/20 0.37
CYP2C9 P11712 2/20 0.37
AKT1 P31749 1/20 0.37
GSR P00390 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL27527850 0.85 THRB (0.36) THRBCYP3A4CYP2C19MAPTTSHR
Phenol SCHEMBL6931537 0.84 THRB (0.40) THRBMEN1KMT2ACYP3A4CYP2C19
Toluene SCHEMBL3759688 0.84 THRB (0.40) THRBCYP3A4CYP2C19MAPTTSHR
Benzene SCHEMBL28161005 0.83 THRB (0.35) THRBCYP3A4CYP2C19MAPTTSHR
Benzophenone SCHEMBL27887676 0.83 ALDH1A1 (0.48) PPARATSHRPPARGALDH1A1AKT1
Styrene SCHEMBL5008696 0.83 ALDH1A1 (0.48) THRBCYP3A4CYP2C19MAPTTSHR
Styrene SCHEMBL6903124 0.83 ALDH1A1 (0.48) THRBCYP3A4CYP2C19MAPTTSHR
Fluorobenzene SCHEMBL28079208 0.83 THRB (0.39) THRBMEN1KMT2ACYP3A4CYP2C19
Toluene SCHEMBL28163624 0.83 THRB (0.39) THRBCYP3A4CYP2C19MAPTTSHR
Bromobenzene SCHEMBL28053133 0.83 NPC1 (0.41) THRBMEN1KMT2ACYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105801410-A Method for synthesizing phenyl acrylate derivative by visible light catalysis of double-catalyst system 南京工业大学 2016-07-27 CN disclosed