Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.51 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.51 |
| ▸ | GLS | O94925 | 2/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27778663 | 0.83 | LMNA (0.57) | LMNAERCC1ERCC4GLSMPO | |
| SCHEMBL1793682 | 0.83 | LMNA (0.78) | LMNAERCC1ERCC4GLSMPO | |
| SCHEMBL327273 | 0.83 | LMNA (0.57) | LMNAERCC1ERCC4GLSMPO | |
| SCHEMBL4117917 | 0.83 | LMNA (0.57) | LMNAERCC1ERCC4GLSMPO | |
| SCHEMBL15602026 | 0.83 | LMNA (0.57) | LMNAERCC1ERCC4GLSMPO | |
| SCHEMBL17629558 | 0.83 | LMNA (0.57) | LMNAERCC1ERCC4GLSMPO | |
| SCHEMBL17864341 | 0.82 | LMNA (0.60) | LMNAERCC1ERCC4GLSMPO | |
| Hydrochloric Acid SCHEMBL5656437 | 0.81 | LMNA (0.76) | LMNAERCC1ERCC4GLSMPO | |
| SCHEMBL5934873 | 0.81 | NOTUM (0.57) | LMNAERCC1ERCC4GLSMPO | |
| SCHEMBL2885383 | 0.81 | LMNA (0.71) | LMNAERCC1ERCC4GLSMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4644390-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | Beyang Therapeutics Co., Ltd. (CN) | 2025-11-05 | — | — | EP | disclosed |
| CN-105658640-A | Alkynyl alcohols and methods of use | 豪夫迈·罗氏有限公司 | 2016-06-08 | — | — | CN | disclosed |