Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.53 |
| ▸ | TACR1 | P25103 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28079605 | 0.90 | RORC (0.48) | RORCTACR1LMNATP53ALDH1A1 | |
| SCHEMBL22570215 | 0.90 | RORC (0.48) | RORCTACR1LMNATP53ALDH1A1 | |
| SCHEMBL28079479 | 0.88 | RORC (0.54) | RORCTACR1LMNATP53MAPT | |
| SCHEMBL28079359 | 0.88 | RORC (0.52) | RORCTACR1TP53SIGMAR1DRD2 | |
| SCHEMBL28079473 | 0.87 | BCHE (0.45) | TACR1LMNAMAPTSIGMAR1DRD2 | |
| SCHEMBL28079474 | 0.86 | MEN1 (0.46) | RORCLMNATP53MAPTBCHE | |
| SCHEMBL28079581 | 0.82 | HRH3 (0.48) | TP53KDM4EALDH1A1 | |
| SCHEMBL28079480 | 0.82 | KMT2A (0.43) | MAPTSIGMAR1SLC6A12KDM4EALDH1A1 | |
| SCHEMBL28079472 | 0.80 | POLB (0.44) | RORCLMNATP53MAPT | |
| SCHEMBL28079355 | 0.79 | MEN1 (0.53) | LMNAMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693598-A | Method for synthesis of 3-piperidone derivatives through iridium catalytic hydrogenation | 中国科学院大连化学物理研究所 | 2016-06-22 | — | — | CN | disclosed |