Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RORC | P51449 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28079511 | 0.90 | RORC (0.56) | RORCLMNATP53MAPTKIF11 | |
| SCHEMBL28079474 | 0.88 | MEN1 (0.46) | POLBRORCLMNATP53MAPT | |
| SCHEMBL22570215 | 0.86 | RORC (0.48) | RORCLMNATP53 | |
| SCHEMBL28079605 | 0.86 | RORC (0.48) | RORCLMNATP53 | |
| SCHEMBL28079479 | 0.84 | RORC (0.54) | RORCLMNATP53MAPT | |
| SCHEMBL28079359 | 0.81 | RORC (0.52) | RORCTP53 | |
| SCHEMBL28079480 | 0.81 | KMT2A (0.43) | POLBMAPT | |
| SCHEMBL28079469 | 0.81 | TP53 (0.46) | RORCTP53MAPTKIF11 | |
| SCHEMBL28079360 | 0.80 | RORC (0.53) | RORCLMNATP53MAPT | |
| SCHEMBL28079357 | 0.80 | SIGMAR1 (0.40) | LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693598-A | Method for synthesis of 3-piperidone derivatives through iridium catalytic hydrogenation | 中国科学院大连化学物理研究所 | 2016-06-22 | — | — | CN | disclosed |