Toluene

Toluene

SCHEMBL28079404

Cc1ccccc1.FCC(F)(F)F

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.58
TSHR P16473 2/20 0.58
LMNA P02545 2/20 0.58
ALOX12 P18054 1/20 0.58
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.37
HTT P42858 2/20 0.35
CYP2C19 P33261 2/20 0.35
MEN1 O00255 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
KIF11 P52732 4/20 0.35
TDP1 Q9NUW8 1/20 0.35
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL8139791 0.85 LMNA (0.52) ACHETSHRLMNAALOX12ALDH1A1
Toluene SCHEMBL8985837 0.82 TSHR (0.55) ACHETSHRLMNAALOX12ALDH1A1
Toluene SCHEMBL28792162 0.80 ACHE (0.69) ACHETSHRLMNAALOX12HPGD
Toluene SCHEMBL6476504 0.80 ACHE (0.69) ACHETSHRLMNAALOX12HPGD
Toluene SCHEMBL28970093 0.78 ACHE (0.65) ACHETSHRLMNAALOX12ALDH1A1
Toluene SCHEMBL10748051 0.78 ACHE (0.65) ACHETSHRLMNAALOX12ALDH1A1
Toluene SCHEMBL10989418 0.76
SCHEMBL12344943 0.76 ACHE (1.00) ACHETSHRLMNAALOX12ALDH1A1
Toluene SCHEMBL175861 0.76 ACHE (1.00) ACHETSHRLMNAALOX12ALDH1A1
Toluene SCHEMBL4535818 0.76 ACHE (1.00) ACHETSHRLMNAALOX12ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105806742-B A kind of gamma ray density measuring system and method for subzero temperature high pressure 西安建筑科技大学 2018-10-02 CN disclosed
CN-205719858-U A kind of gamma ray density for subzero temperature high pressure measures system 西安建筑科技大学 2016-11-23 CN disclosed
CN-105806742-A Gamma ray density measuring system and method for minus temperature and high pressure 西安建筑科技大学 2016-07-27 CN disclosed