Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | CFD | P00746 | 13/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538551 | 0.81 | CNR2 (0.47) | PARP1KDM4E | |
| SCHEMBL28079256 | 0.79 | ELANE (0.56) | ELANEPARP1CFDSCN9A | |
| SCHEMBL8877216 | 0.78 | ELANE (0.55) | ELANEPARP1CFDSCN9A | |
| SCHEMBL7550775 | 0.77 | CNR2 (0.62) | ELANEPARP1POLBKDM4E | |
| SCHEMBL29358880 | 0.77 | HSD17B10 (0.61) | ELANEPARP1CFDSCN9AKDM4E | |
| SCHEMBL12479559 | 0.77 | HSD17B10 (0.61) | ELANEPARP1CFDSCN9AKDM4E | |
| SCHEMBL5433258 | 0.76 | CNR1 (0.57) | ELANEPARP1CFD | |
| SCHEMBL18967134 | 0.75 | ELANE (0.52) | ELANEPARP1CFDSCN9A | |
| SCHEMBL3775553 | 0.75 | PTGER4 (0.60) | ELANEPARP1SCN9AKDM4E | |
| SCHEMBL31647277 | 0.75 | PTGER4 (0.60) | ELANEPARP1SCN9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658640-A | Alkynyl alcohols and methods of use | 豪夫迈·罗氏有限公司 | 2016-06-08 | — | — | CN | disclosed |