Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.57 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | CFD | P00746 | 13/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.47 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13691221 | 0.91 | CNR1 (0.53) | CNR1ELANEPARP1CFDACHE | |
| SCHEMBL8719218 | 0.87 | CNR1 (0.53) | CNR1ACHECNR2SSTR4PADI4 | |
| SCHEMBL31429317 | 0.87 | CNR1 (0.53) | CNR1ACHECNR2SSTR4PADI4 | |
| SCHEMBL8713428 | 0.86 | CNR1 (0.52) | CNR1ACHECNR2SSTR4PADI4 | |
| SCHEMBL31429457 | 0.82 | CNR1 (0.54) | CNR1ELANEACHECNR2SSTR4 | |
| SCHEMBL24437187 | 0.82 | CNR1 (0.56) | CNR1ACHECNR2SSTR4PADI4 | |
| SCHEMBL31429426 | 0.82 | CNR1 (0.56) | CNR1ACHECNR2SSTR4PADI4 | |
| SCHEMBL4052657 | 0.81 | CNR1 (0.61) | CNR1ACHECNR2SSTR4PADI4 | |
| SCHEMBL28079256 | 0.80 | ELANE (0.56) | CNR1ELANEPARP1CFDCNR2 | |
| SCHEMBL8877216 | 0.79 | ELANE (0.55) | CNR1ELANEPARP1CFDCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007530590-A | — | — | 2007-11-01 | — | — | JP | claimed |
| EP-1735306-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | Memory Pharmaceuticals Corporation (US) | 2006-12-27 | — | — | EP | claimed |
| WO-2005092890-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2005-10-06 | — | — | WO | claimed |
| EP-1735306-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | Memory Pharmaceuticals Corporation (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005092890-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2005-10-06 | — | — | WO | disclosed |
| US-5684003-A | GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |