Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697586 | 0.88 | MAOB (0.55) | MAOBKMT2AMEN1MAOANPC1 | |
| SCHEMBL29742938 | 0.88 | MAOB (0.55) | MAOBKMT2AMEN1MAOANPC1 | |
| SCHEMBL7927459 | 0.85 | MAOB (0.52) | MAOBKMT2AMEN1MAOANPC1 | |
| SCHEMBL2095019 | 0.85 | MAOB (0.52) | MAOBKMT2AMEN1MAOANPC1 | |
| SCHEMBL2557596 | 0.83 | MAOB (0.51) | MAOBKMT2AMEN1MAOANPC1 | |
| SCHEMBL1619240 | 0.83 | MAPT (0.52) | MAOBKMT2AMEN1MAOANPC1 | |
| SCHEMBL2037979 | 0.82 | KMT2A (0.54) | MAOBKMT2AMEN1MAOANPC1 | |
| SCHEMBL30837232 | 0.79 | ABL1 (0.55) | MAOBNPC1RAB9AMAPT | |
| SCHEMBL2277217 | 0.79 | KMT2A (0.54) | MAOBKMT2AMEN1MAOANPC1 | |
| SCHEMBL5331403 | 0.78 | MAOB (0.53) | MAOBKMT2AMEN1MAOANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105801390-A | Method for synthesizing 2,4-dibromo-3-difluoromethoxy acetophenone | 浙江中欣氟材股份有限公司 | 2016-07-27 | — | — | CN | claimed |