SCHEMBL30837232

SCHEMBL30837232

CC(=O)c1cccc(-c2cccc(OC(F)(F)F)c2)c1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 4/20 0.55
DHODH Q02127 4/20 0.47
DYRK1A Q13627 1/20 0.47
MAOB P27338 2/20 0.47
MAPT P10636 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
FYN P06241 1/20 0.47
SLC6A7 Q99884 1/20 0.46
SLC13A5 Q86YT5 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
XDH P47989 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29742938 0.90 MAOB (0.55) ABL1MAOBNPC1RAB9A
SCHEMBL697586 0.90 MAOB (0.55) ABL1MAOBNPC1RAB9A
SCHEMBL25602455 0.89 ABL1 (0.60) ABL1MAPTTDP1NPC1RAB9A
SCHEMBL5515377 0.86 KMO (0.56) DHODHSLC13A5NPC1RAB9A
SCHEMBL3722117 0.84 DYRK1A (0.62) ABL1DYRK1AMAPTSLC6A7SLC13A5
SCHEMBL30837176 0.80 HSD17B2 (0.61) DYRK1AFYNNPC1RAB9A
SCHEMBL10389918 0.79 MAP4K4 (0.59) MAPTTDP1FYN
SCHEMBL28079445 0.79 MAOB (0.54) MAOBMAPTNPC1RAB9A
SCHEMBL25602485 0.79 IDO1 (0.46) ABL1
SCHEMBL14980381 0.78 ALDH1A1 (0.59) ABL1FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4573086-A1 METHANOGEN INHIBITORS Agrizeronz Limited Partnership (NZ) 2025-06-25 EP disclosed
CN-119998272-A Methanogen inhibitors 阿格里泽伦茨有限合伙公司 2025-05-13 CN disclosed
WO-2024039250-A1 METHANOGEN INHIBITORS PASTORAL GREENHOUSE GAS RESEARCH LIMITED (NZ) 2024-02-22 WO disclosed