SCHEMBL697586

SCHEMBL697586

CC(=O)c1cccc(OC(F)(F)F)c1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.55
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
TAS1R3 Q7RTX0 1/20 0.52
TAS1R1 Q7RTX1 1/20 0.52
TAS1R2 Q8TE23 1/20 0.52
KAT6A Q92794 2/20 0.51
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
HDAC8 Q9BY41 1/20 0.50
ABL1 P00519 1/20 0.50
ALDH1A1 P00352 1/20 0.49
TP53 P04637 1/20 0.48
GPR139 Q6DWJ6 1/20 0.48
MAOA P21397 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29742938 1.00 MAOB (0.55) MAOBMEN1KMT2ATAS1R3TAS1R1
SCHEMBL30837232 0.90 ABL1 (0.55) MAOBNPC1RAB9AABL1
SCHEMBL28079445 0.88 MAOB (0.54) MAOBMEN1KMT2ANPC1RAB9A
SCHEMBL7927459 0.86 MAOB (0.52) MAOBMEN1KMT2ANPC1RAB9A
SCHEMBL17065159 0.86 CES2 (0.51) MAOBTAS1R3TAS1R1TAS1R2KAT6A
SCHEMBL2095019 0.86 MAOB (0.52) MAOBMEN1KMT2ANPC1RAB9A
SCHEMBL29236792 0.86 MAOB (0.58) MAOBMEN1KMT2ATAS1R3TAS1R1
SCHEMBL690501 0.85 KAT6A (0.54) MAOBTAS1R3TAS1R1TAS1R2KAT6A
SCHEMBL16959752 0.85 TAS1R3 (0.48) MAOBTAS1R3TAS1R1TAS1R2KAT6A
SCHEMBL2557596 0.85 MAOB (0.51) MAOBMEN1KMT2AKAT6ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 347 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612033-B2 Methods for delivering compounds into a cell IMARX PHARMACEUTICAL CORP. (US) 2009-11-03 US claimed
EP-1015039-B1 OXYGEN DELIVERY AGENTS AND USES FOR THE SAME IMARX PHARMACEUTICAL CORP (US) 2008-08-27 EP claimed
EP-0935415-B1 IN VITRO METHODS FOR DELIVERING NUCLEIC ACIDS INTO A CELL IMARX PHARMACEUTICAL CORP (US) 2006-11-22 EP claimed
US-7105151-B2 Oxygen delivery agents and uses for the same IMARX THERAPEUTICS, INC. (US) 2006-09-12 US claimed
US-20040176473-A1 Methods for delivering compounds into a cell IMARX PHARMACEUTICAL CORP. 2004-09-09 US claimed
US-6743779-B1 NUCLEIC ACID SEQUENCE AND A FLUORINATED COMPOUND AND A LIPID CARRIER. IMARX PHARMACEUTICAL CORP. 2004-06-01 US claimed
US-6638767-B2 Mixture containing organic halide IMARX PHARMACEUTICAL CORPORATION 2003-10-28 US claimed
US-20030120204-A1 Oxygen delivery agents and uses for the same CEREVAST THERAPEUTICS, INC. 2003-06-26 US claimed
EP-1015039-A4 OXYGEN DELIVERY AGENTS AND USES FOR THE SAME IMARX PHARMACEUTICAL CORP (US) 2002-09-11 EP claimed
EP-0935415-A4 METHODS FOR DELIVERING COMPOUNDS INTO A CELL IMARX PHARMACEUTICAL CORP (US) 2002-08-14 EP claimed
US-20010031740-A1 Methods for delivering compounds into a cell IMARX PHARMACEUTICAL CORPORATION 2001-10-18 US claimed
US-6143276-A ADMINISTERING TO THE PATIENT A COMPOSITION COMPRISING A BIOACTIVE AGENT AND A GASEOUS PRECURSOR CAPABLE OF UNDERGOING PHASE TRANSITION TO A GAS AT A REGION OF ELEVATED TEMPERATURE IN THE PATIENT IMARX PHARMACEUTICAL CORP. (US) 2000-11-07 US claimed
EP-1046394-A2 Novel compositions useful for delivering compounds into a cell ImaRx Pharmaceutical Corp. (US) 2000-10-25 EP claimed
EP-1015039-A1 OXYGEN DELIVERY AGENTS AND USES FOR THE SAME IMARX PHARMACEUTICAL CORP. (US) 2000-07-05 EP claimed
EP-0988061-A1 METHODS FOR DELIVERING BIOACTIVE AGENTS IMARX PHARMACEUTICAL CORP. (US) 2000-03-29 EP claimed
EP-0935415-A1 METHODS FOR DELIVERING COMPOUNDS INTO A CELL IMARX PHARMACEUTICAL CORP. (US) 1999-08-18 EP claimed
WO-1999025385-A1 A METHOD OF INCREASING NUCLEIC ACID SYNTHESIS WITH ULTRASOUND IMARX PHARMACEUTICAL CORP. (US) 1999-05-27 WO claimed
WO-1998057670-A1 OXYGEN DELIVERY AGENTS AND USES FOR THE SAME IMARX PHARMACEUTICAL CORP. (US) 1998-12-23 WO claimed
WO-1998042384-A1 METHODS FOR DELIVERING BIOACTIVE AGENTS IMARX PHARMACEUTICAL CORP. (US) 1998-10-01 WO claimed
WO-1997040679-A1 METHODS FOR DELIVERING COMPOUNDS INTO A CELL IMARX PHARMACEUTICAL CORP. (US) 1997-11-06 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040176473-A1 Methods for delivering compounds into a cell ABCB4, NPC1L1, IAPP MAOB 3210/4885MEN1 1692/4885KMT2A 4067/4885
US-20010031740-A1 Methods for delivering compounds into a cell ABCB4, NPC1L1, IAPP MAOB 3210/4885MEN1 1692/4885KMT2A 4067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.