Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 3/20 | 0.57 |
| ▸ | BLM | P54132 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | CASP1 | P29466 | 2/20 | 0.57 |
| ▸ | CASP7 | P55210 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6238059 | 0.91 | MAPT (0.62) | MEN1KMT2ATDP1MAPTPOLB | |
| SCHEMBL12578244 | 0.85 | MAPT (0.58) | MEN1KMT2ATDP1MAPTPOLB | |
| SCHEMBL28079386 | 0.83 | MEN1 (0.81) | MEN1KMT2ATDP1MAPTPOLB | |
| SCHEMBL8802391 | 0.76 | MAPT (0.51) | MEN1KMT2ATDP1MAPTPOLB | |
| SCHEMBL27734202 | 0.75 | MEN1 (1.00) | MEN1KMT2ATDP1MAPTPOLB | |
| SCHEMBL12207312 | 0.74 | TDP1 (0.50) | MEN1KMT2ATDP1MAPTKDM4E | |
| SCHEMBL12207290 | 0.74 | TDP1 (0.50) | MEN1KMT2ATDP1MAPTKDM4E | |
| SCHEMBL28079390 | 0.74 | PDE10A (0.51) | MEN1KMT2ATDP1MAPTKDM4E | |
| SCHEMBL4750618 | 0.73 | TDP1 (0.49) | MEN1KMT2ATDP1MAPTKDM4E | |
| SCHEMBL14842553 | 0.73 | KDM4E (0.62) | MEN1KMT2ATDP1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693632-B | A kind of preparation method of polysubstituted quinoxaline derivant | 华侨大学 | 2018-04-17 | — | — | CN | disclosed |
| CN-105693632-A | Preparation method of polysubstitution quinoxalin derivatives | 华侨大学 | 2016-06-22 | — | — | CN | disclosed |