Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.81 |
| ▸ | POLB | P06746 | 5/20 | 0.81 |
| ▸ | MAPT | P10636 | 5/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.81 |
| ▸ | RECQL | P46063 | 4/20 | 0.81 |
| ▸ | BLM | P54132 | 4/20 | 0.81 |
| ▸ | HPGD | P15428 | 3/20 | 0.81 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.81 |
| ▸ | PKM | P14618 | 2/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.81 |
| ▸ | CASP1 | P29466 | 2/20 | 0.81 |
| ▸ | CASP7 | P55210 | 2/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
| ▸ | PIK3R1 | P27986 | 8/20 | 0.71 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27734202 | 0.90 | MEN1 (1.00) | MEN1KMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL28079538 | 0.83 | MEN1 (0.57) | MEN1KMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL27734571 | 0.83 | PIK3R1 (1.00) | MEN1KMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL15665921 | 0.81 | ALDH1A1 (0.87) | MEN1KMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL29382173 | 0.79 | KDM4E (0.74) | MEN1KMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL732131 | 0.79 | KDM4E (0.74) | MEN1KMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL8006645 | 0.78 | ALDH1A1 (0.75) | MEN1KMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL503307 | 0.78 | MEN1 (0.75) | MEN1KMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL865711 | 0.77 | KDM4E (0.71) | MEN1KMT2ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL13950894 | 0.77 | KDM4E (0.78) | MEN1KMT2ATDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693632-B | A kind of preparation method of polysubstituted quinoxaline derivant | 华侨大学 | 2018-04-17 | — | — | CN | disclosed |
| CN-105693632-A | Preparation method of polysubstitution quinoxalin derivatives | 华侨大学 | 2016-06-22 | — | — | CN | disclosed |