Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 12/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28536837 | 0.84 | AKR1C3 (0.41) | GSK3BPTPN1AKR1C3AKR1C2ALPL | |
| SCHEMBL8343669 | 0.83 | PTPN1 (0.59) | GSK3BPTPN1ALPLPLAAALPG | |
| SCHEMBL3995406 | 0.83 | GSK3B (0.59) | GSK3BPTPN1 | |
| SCHEMBL29628383 | 0.78 | GSK3B (0.57) | GSK3BPTPN1 | |
| SCHEMBL883208 | 0.78 | GSK3B (0.57) | GSK3BPTPN1 | |
| SCHEMBL8004853 | 0.78 | GSK3B (0.57) | GSK3BPTPN1 | |
| SCHEMBL2953875 | 0.78 | PTPN1 (0.57) | GSK3BPTPN1 | |
| SCHEMBL6120966 | 0.78 | GSK3B (0.53) | GSK3BPTPN1 | |
| SCHEMBL11527527 | 0.78 | GSK3B (0.48) | GSK3BPTPN1 | |
| SCHEMBL1812684 | 0.77 | CA12 (0.64) | AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105801390-A | Method for synthesizing 2,4-dibromo-3-difluoromethoxy acetophenone | 浙江中欣氟材股份有限公司 | 2016-07-27 | — | — | CN | claimed |
| CN-105801482-A | Method for preparing 1-cyclopropyl-4-oxo-7-bromine-8-difluoromethoxy-1,4-dihydro-quinoline-3-nonanoic acid-ethyl ester | 浙江中欣氟材股份有限公司 | 2016-07-27 | — | — | CN | claimed |
| CN-105801390-A | Method for synthesizing 2,4-dibromo-3-difluoromethoxy acetophenone | 浙江中欣氟材股份有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-105801390-A | Method for synthesizing 2,4-dibromo-3-difluoromethoxy acetophenone | 浙江中欣氟材股份有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-105801482-A | Method for preparing 1-cyclopropyl-4-oxo-7-bromine-8-difluoromethoxy-1,4-dihydro-quinoline-3-nonanoic acid-ethyl ester | 浙江中欣氟材股份有限公司 | 2016-07-27 | — | — | CN | disclosed |