SCHEMBL1812684

SCHEMBL1812684

O=C(O)c1ccc(Br)c(O)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.64
CA1 P00915 5/20 0.64
CA2 P00918 5/20 0.64
CA6 P23280 5/20 0.64
CA9 Q16790 5/20 0.64
CA7 P43166 4/20 0.64
CA14 Q9ULX7 4/20 0.64
CA4 P22748 3/20 0.64
KDM4E B2RXH2 2/20 0.64
MAPT P10636 2/20 0.64
POLB P06746 1/20 0.64
GAA P10253 1/20 0.64
PTGS2 P35354 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
TTR P02766 2/20 0.52
CA3 P07451 3/20 0.50
CA5A P35218 3/20 0.50
CA5B Q9Y2D0 3/20 0.50
TP53 P04637 2/20 0.50
HPGD P15428 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL6507901 0.98 CA12 (0.61) CA12CA1CA2CA6CA9
SCHEMBL30436340 0.82 CA12 (0.64) CA12CA1CA2CA6CA9
SCHEMBL312791 0.82 CA12 (0.64) CA12CA1CA2CA6CA9
SCHEMBL29810232 0.81 TTR (0.56) CA12CA1CA2CA6CA9
SCHEMBL588825 0.81 TTR (0.56) CA12CA1CA2CA6CA9
SCHEMBL8252798 0.80 LCK (0.53) CA12CA1CA2CA9CA14
SCHEMBL10034774 0.80 PKM (0.50) CA2MAPTPOLBCA5AALDH1A1
SCHEMBL2771199 0.78 CA12 (0.73) CA12CA1CA2CA6CA9
Protocatechuic Acid SCHEMBL39435 0.78 CA12 (1.00) CA12CA1CA2CA6CA9
Protocatechuic Acid SCHEMBL30030432 0.78 CA12 (1.00) CA12CA1CA2CA6CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 319 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118252934-A Application of HDC as stomach cancer cisplatin drug-resistant target 浙江省肿瘤医院 2024-06-28 CN claimed
CN-114714724-B Hot melt adhesive transfer film and preparation method thereof 云阳金田塑业有限公司 2023-11-17 CN claimed
CN-114714724-A Hot melt adhesive transfer film and preparation method thereof 云阳金田塑业有限公司 2022-07-08 CN claimed
US-20050080260-A1 Preparation of prodrugs for selective drug delivery LUMINIDE 2005-04-14 US claimed
EP-4076460-B1 1,4-DIHYDRO-2H-SPIRO[ISOQUINOLINE-3,4'-PIPERIDINE DERIVATIVES AS PRMT5 INHIBITORS FOR THE TREATMENT OF CANCER MERCK SHARP & DOHME LLC (US) 2026-01-21 EP disclosed
US-12509460-B2 Methods and compositions for modulating splicing SKYHAWK THERAPEUTICS, INC. (US) 2025-12-30 US disclosed
EP-4663626-A1 IMINE COMPOUNDS AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF Bio Genuine (Shanghai) Biotech Co., Ltd (CN) 2025-12-17 EP disclosed
EP-4653864-A1 SEPARATION AGENT Daicel Corporation (JP) 2025-11-26 EP disclosed
US-12441730-B2 PRMT5 inhibitors MERCK SHARP & DOHME LLC (US) 2025-10-14 US disclosed
US-20250282776-A1 Bicyclic TLR7 Agonists and Uses Thereof BRISTOL-MYERS SQUIBB COMPANY (US) 2025-09-11 US disclosed
US-12403137-B2 Compounds and methods of use TANGO THERAPEUTICS, INC. (US) 2025-09-02 US disclosed
CN-119948034-A Novel peptide-based nitrile compound and application thereof 上海壹迪生物技术有限公司 2025-05-06 CN disclosed
US-4886869-A OPTIONALLY SUBSTITUTED WITH-3-HYDROXY BENZOIC ACID; RIGIDITY, IMPACT STRENGTH AND ELONGATION BAYER AKTIENGESELLSCHAFT (DE) 1989-12-12 US disclosed
WO-1989009833-A1 LUMINIDE AND MACROLUMINIDE CLASS OF PHARMACEUTICALS MILLS RANDELL L (US) 1989-10-19 WO disclosed
EP-0044205-B1 POLYESTER OF 6-HYDROXY-2-NAPHTHOIC ACID AND METAHYDROXY BENZOIC ACID CAPABLE OF READILY UNDERGOING MELT PROCESSING CELANESE CORPORATION (US) 1985-04-10 EP disclosed
EP-0006125-B1 PHOTOPOLYMERISABLE MIXTURE AND LIGHT-SENSITIVE COATING MATERIAL HOECHST AKTIENGESELLSCHAFT (DE) 1983-05-11 EP disclosed
US-4337190-A Polyester of 6-hydroxy-2-naphthoic acid and meta-hydroxy benzoic acid capable of readily undergoing melt processing CELANESE CORPORATION (US) 1982-06-29 US disclosed
EP-0044205-A1 Polyester of 6-hydroxy-2-naphthoic acid and metahydroxy benzoic acid capable of readily undergoing melt processing CELANESE CORPORATION (US) 1982-01-20 EP disclosed
US-4245030-A Photopolymerizable mixture containing improved plasticizer HOECHST AKTIENGESELLSCHAFT (DE) 1981-01-13 US disclosed
EP-0006125-A1 Photopolymerisable mixture and light-sensitive coating material HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050080260-A1 Preparation of prodrugs for selective drug delivery APEH, PAH, ALAD CA12 1448/4885CA1 2423/4885CA2 3018/4885
US-20250282776-A1 Bicyclic TLR7 Agonists and Uses Thereof TLR7, TLR9, TLR1 CA12 3176/4885CA1 4343/4885CA2 4074/4885
US-12509460-B2 Methods and compositions for modulating splicing SF3B1, RTCB, RBM17 CA12 4814/4885CA1 4526/4885CA2 4755/4885
US-12403137-B2 Compounds and methods of use XDH, LPXN, F12 CA12 1141/4885CA1 1360/4885CA2 1078/4885
US-12441730-B2 PRMT5 inhibitors PRMT5, PRMT1, PRMT3 CA12 4534/4885CA1 3927/4885CA2 3181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.