Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28079387 | 0.84 | L3MBTL1 (0.58) | TDP1L3MBTL1NPY5RPDE10APOLB | |
| SCHEMBL12578244 | 0.78 | MAPT (0.58) | TDP1L3MBTL1MAPTMAPK1RAB9A | |
| SCHEMBL12146715 | 0.74 | TDP1 (0.48) | TDP1L3MBTL1NPY5RPDE10APOLB | |
| SCHEMBL12146723 | 0.74 | TDP1 (0.48) | TDP1L3MBTL1NPY5RPDE10APOLB | |
| SCHEMBL8802391 | 0.72 | MAPT (0.51) | TDP1L3MBTL1MAPTMAPK1RAB9A | |
| SCHEMBL12146721 | 0.72 | TDP1 (0.46) | TDP1L3MBTL1NPY5RPDE10ALCK | |
| SCHEMBL1459827 | 0.72 | NPY5R (0.45) | TDP1NPY5RMAPTMAPK1RAB9A | |
| SCHEMBL12146725 | 0.71 | TDP1 (0.45) | TDP1L3MBTL1NPY5RPDE10ALCK | |
| SCHEMBL1459871 | 0.71 | HRH4 (0.55) | TDP1L3MBTL1NPY5RMAPTMAPK1 | |
| SCHEMBL14842553 | 0.70 | KDM4E (0.62) | TDP1L3MBTL1MAPTMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693632-B | A kind of preparation method of polysubstituted quinoxaline derivant | 华侨大学 | 2018-04-17 | — | — | CN | disclosed |
| CN-105693632-A | Preparation method of polysubstitution quinoxalin derivatives | 华侨大学 | 2016-06-22 | — | — | CN | disclosed |