Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12146723 | 0.89 | TDP1 (0.48) | L3MBTL1TDP1PDE10ALCKKDM4E | |
| SCHEMBL12146715 | 0.89 | TDP1 (0.48) | L3MBTL1TDP1PDE10ALCKKDM4E | |
| SCHEMBL12146721 | 0.87 | TDP1 (0.46) | L3MBTL1TDP1PDE10ALCKKDM4E | |
| SCHEMBL12146725 | 0.85 | TDP1 (0.45) | L3MBTL1TDP1PDE10ALCKKDM4E | |
| SCHEMBL28079612 | 0.84 | TDP1 (0.49) | L3MBTL1TDP1PDE10ALCKKDM4E | |
| SCHEMBL14565646 | 0.82 | HPGD (0.66) | L3MBTL1TDP1KDM4EPKMLMNA | |
| SCHEMBL14565645 | 0.82 | HPGD (0.66) | L3MBTL1TDP1KDM4EPKMLMNA | |
| SCHEMBL28638010 | 0.82 | PDE10A (0.46) | L3MBTL1TDP1PDE10AKDM4EPKM | |
| SCHEMBL1933769 | 0.81 | TDP1 (0.46) | L3MBTL1TDP1PDE10ALCKNPY5R | |
| SCHEMBL7699018 | 0.79 | PDE10A (0.49) | L3MBTL1TDP1PDE10AKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693632-B | A kind of preparation method of polysubstituted quinoxaline derivant | 华侨大学 | 2018-04-17 | — | — | CN | disclosed |
| CN-105693632-A | Preparation method of polysubstitution quinoxalin derivatives | 华侨大学 | 2016-06-22 | — | — | CN | disclosed |