Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16054002 | 0.91 | LMNA (0.77) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL3539705 | 0.88 | LMNA (0.69) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL2552124 | 0.85 | LMNA (0.72) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL28831574 | 0.82 | ALDH1A1 (0.62) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL7040997 | 0.82 | LMNA (0.69) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL9246238 | 0.81 | LMNA (0.72) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL28024114 | 0.81 | POLB (0.73) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL2546137 | 0.79 | MAPT (0.64) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL18376420 | 0.78 | MAPT (0.75) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL18779403 | 0.78 | LMNA (0.75) | ALDH1A1LMNAL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105801582-A | Novel dihydro pteridinone derivative, preparing method thereof and application to medicine | 合肥工业大学 | 2016-07-27 | — | — | CN | disclosed |