SCHEMBL28079807

SCHEMBL28079807

O=CCc1ccc(-c2cccs2)s1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.61
DPP4 P27487 4/20 0.59
ALDH1A1 P00352 5/20 0.49
KDM4E B2RXH2 4/20 0.49
GAA P10253 3/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
LMNA P02545 2/20 0.49
GLA P06280 2/20 0.49
MAPT P10636 2/20 0.49
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
MEN1 O00255 2/20 0.47
POLB P06746 2/20 0.47
HPGD P15428 2/20 0.47
CASP1 P29466 2/20 0.47
CASP7 P55210 2/20 0.47
KMT2A Q03164 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
HSD17B10 Q99714 2/20 0.47
TP53 P04637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL976339 0.82 LTA4H (0.61) LTA4HDPP4ALDH1A1KDM4EGAA
SCHEMBL21823759 0.79 LTA4H (0.71) LTA4HDPP4ALDH1A1KDM4EGAA
SCHEMBL498364 0.77 DPP4 (0.61) LTA4HDPP4ALDH1A1KDM4EGAA
SCHEMBL21386864 0.76 DPP4 (0.66) LTA4HDPP4ALDH1A1KDM4EGAA
SCHEMBL286875 0.76
SCHEMBL2690127 0.76 LTA4H (1.00) LTA4HDPP4ALDH1A1KDM4EGAA
SCHEMBL406832 0.76 DPP4 (0.96) LTA4HDPP4ALDH1A1KDM4EGAA
SCHEMBL8575790 0.76 LTA4H (0.67) LTA4HDPP4ALDH1A1KDM4EGAA
SCHEMBL799550 0.76 LTA4H (0.67) LTA4HDPP4ALDH1A1KDM4EGAA
SCHEMBL12630759 0.75 LTA4H (0.61) LTA4HDPP4ALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118420606-A Fluorescent probe and application thereof in viscosity detection 天津理工大学 2024-08-02 CN claimed
CN-115340554-B Pyrazolopyrimidine compound, preparation method thereof and application of pyrazolopyrimidine compound as fluorescent probe 华南农业大学 2023-04-18 CN claimed
CN-115340554-A Pyrazolopyrimidine compound, preparation method thereof and application of pyrazolopyrimidine compound as fluorescent probe 华南农业大学 2022-11-15 CN claimed
CN-118420606-A Fluorescent probe and application thereof in viscosity detection 天津理工大学 2024-08-02 CN disclosed
CN-118420606-A Fluorescent probe and application thereof in viscosity detection 天津理工大学 2024-08-02 CN disclosed
CN-115340554-B Pyrazolopyrimidine compound, preparation method thereof and application of pyrazolopyrimidine compound as fluorescent probe 华南农业大学 2023-04-18 CN disclosed
CN-115340554-A Pyrazolopyrimidine compound, preparation method thereof and application of pyrazolopyrimidine compound as fluorescent probe 华南农业大学 2022-11-15 CN disclosed
CN-104387790-B A kind of benzindole salt dyestuff of thienyl-containing group and its production and use 北京科技大学 2016-08-24 CN disclosed