SCHEMBL8575790

SCHEMBL8575790

CCc1ccc(-c2cccs2)s1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.67
DPP4 P27487 4/20 0.65
ALDH1A1 P00352 4/20 0.49
KDM4E B2RXH2 4/20 0.49
RAB9A P51151 4/20 0.49
NPC1 O15118 3/20 0.49
GAA P10253 3/20 0.49
LMNA P02545 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
GLA P06280 1/20 0.49
MAPT P10636 1/20 0.49
HPGD P15428 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HSD17B10 Q99714 2/20 0.43
MEN1 O00255 1/20 0.43
TP53 P04637 1/20 0.43
POLB P06746 1/20 0.43
NFKB1 P19838 1/20 0.43
MAPK1 P28482 1/20 0.43
CASP1 P29466 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2031590 0.98 DPP4 (0.68) LTA4HDPP4ALDH1A1KDM4ERAB9A
SCHEMBL21386863 0.98 DPP4 (0.68) LTA4HDPP4ALDH1A1KDM4ERAB9A
SCHEMBL4862372 0.85 LTA4H (0.62) LTA4HDPP4ALDH1A1KDM4ERAB9A
SCHEMBL21823759 0.83 LTA4H (0.71) LTA4HDPP4ALDH1A1KDM4ERAB9A
SCHEMBL4854006 0.83 DPP4 (0.64) LTA4HDPP4ALDH1A1KDM4ERAB9A
SCHEMBL4853338 0.83 DPP4 (0.64) LTA4HDPP4ALDH1A1KDM4ERAB9A
SCHEMBL13621245 0.82 DPP4 (0.41) LTA4HDPP4ALDH1A1KDM4ERAB9A
SCHEMBL26354789 0.81 DPP4 (0.47) LTA4HDPP4ALDH1A1KDM4ERAB9A
SCHEMBL18876409 0.80 LTA4H (0.57) LTA4HDPP4ALDH1A1KDM4ERAB9A
SCHEMBL2027946 0.80 DPP4 (0.44) LTA4HDPP4ALDH1A1KDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11586060-B2 Optical filter with light source SOLUTIA CANADA INC. (CA) 2023-02-21 US disclosed
US-10770665-B2 Fluorinated dye compounds for organic solar cells NEXT ENERGY TECHNOLOGY, INC. (US) 2020-09-08 US disclosed
US-20180114930-A1 FLUORINATED DYE COMPOUNDS FOR ORGANIC SOLAR CELLS NEXT ENERGY TECHNOLOGIES, INC. (US) 2018-04-26 US disclosed
US-20140135485-A1 6-11 BICYCLIC KETOLIDE DERIVATIVES ENANTA PHARMACEUTICALS, INC. (US) 2014-05-15 US disclosed
US-8524738-B2 Quinolinones and quinoxalinones as antibacterial composition TOYAMA CHEMICAL CO., LTD. (JP) 2013-09-03 US disclosed
US-8524738-B2 Quinolinones and quinoxalinones as antibacterial composition TOYAMA CHEMICAL CO., LTD. (JP) 2013-09-03 US disclosed
US-8481696-B2 Glycosylated glycopeptide antibiotic derivatives SHIONOGI & CO., LTD. (JP) 2013-07-09 US disclosed
US-8481696-B2 Glycosylated glycopeptide antibiotic derivatives SHIONOGI & CO., LTD. (JP) 2013-07-09 US disclosed
US-8329694-B2 Quinoxalinones as antibacterial composition TOYAMA CHEMICAL CO., LTD. (JP) 2012-12-11 US disclosed
US-8329694-B2 Quinoxalinones as antibacterial composition TOYAMA CHEMICAL CO., LTD. (JP) 2012-12-11 US disclosed
US-20070244160-A1 6-11 Bicyclic Ketolide Derivatives OR YAT SUN 2007-10-18 US disclosed
US-20070232554-A1 3,6-Bridged 9,12-oxolides ENATA PHARMACEUTICALS, INC. 2007-10-04 US disclosed
US-7273853-B2 6-11 bicyclic ketolide derivatives ENANTA PHARMACEUTICALS, INC. (US) 2007-09-25 US disclosed
US-7241780-B2 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method BRISTOLS-MYERS SQUIBB COMPANY (US) 2007-07-10 US disclosed
US-7229972-B2 Semisynthetic trimethylenedioxy-erythromycin derivatives and their use in treating bacterial infections and cystic fibrosis; preparation ENANTA PHARMACEUTICALS, INC. (US) 2007-06-12 US disclosed
US-7196080-B2 Respiratory system disordeers; chronic obstructive pulminary disease ASTELLAS PHARMA INC. (JP) 2007-03-27 US disclosed
US-20070015797-A1 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method CHENG PETER T 2007-01-18 US disclosed
US-5753692-A PLANT EXTRACTS, IMMUNOSTIMULANTS TREATING IMMUNODEFICIENCY DISEASES INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1998-05-19 US disclosed
US-5747525-A ANTITUMOR AGENTS OF OLIGOMERS OF THIOPHENE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1998-05-05 US disclosed
US-5602170-A ADMINISTERING ANTIIFLAMMATORY AGENT INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1997-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140135485-A1 6-11 BICYCLIC KETOLIDE DERIVATIVES AKR1C2, AKR1C3, AKR1C1 LTA4H 414/4885DPP4 471/4885ALDH1A1 452/4885
US-10770665-B2 Fluorinated dye compounds for organic solar cells OR10J3, EPCAM, KCNN2 LTA4H 2604/4885DPP4 2837/4885ALDH1A1 625/4885
US-20070244160-A1 6-11 Bicyclic Ketolide Derivatives AKR1C2, AKR1C3, AKR1C1 LTA4H 414/4885DPP4 471/4885ALDH1A1 452/4885
US-20070232554-A1 3,6-Bridged 9,12-oxolides CYP2C9, CYP2C19, CYP2D6 LTA4H 527/4885DPP4 419/4885ALDH1A1 353/4885
US-20070015797-A1 Substituted acid derivatives useful as antidiabetic and antiobesity agents and method GPR119, LIPC, ACACA LTA4H 3219/4885DPP4 144/4885ALDH1A1 1055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.