Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.96 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.96 |
| ▸ | ALPI | P09923 | 1/20 | 0.96 |
| ▸ | PKM | P14618 | 1/20 | 0.96 |
| ▸ | XIAP | P98170 | 1/20 | 0.96 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.67 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.67 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.67 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.56 |
| ▸ | FYN | P06241 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine SCHEMBL43671 | 0.98 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Phenylalanine SCHEMBL1331985 | 0.98 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Phenylalanine SCHEMBL8118 | 0.98 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine SCHEMBL8119 | 0.98 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Phenylalanine SCHEMBL385804 | 0.98 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL23159186 | 0.98 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Phenylalanine SCHEMBL1449124 | 0.98 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Phenylalanine SCHEMBL16398196 | 0.98 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| D-Phenylalanine SCHEMBL837632 | 0.98 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine SCHEMBL16398197 | 0.98 | SLC7A5 (1.00) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105647824-A | In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris | 斯克利普斯研究院 | 2016-06-08 | — | — | CN | claimed |
| CN-110121340-A | Formulation of pegylated arginine deiminase | 波拉里集团 | 2019-08-13 | — | — | CN | disclosed |
| CN-109863162-A | Engineered imine reductases and methods for reductive amination of ketone and amine compounds | 科德克希思公司 | 2019-06-07 | — | — | CN | disclosed |
| CN-109715182-A | It is engineered β-glucosyl enzym and glucosylation method | 科德克希思公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-109715817-A | Hydroxylated biocatalyst and method for compound | 科德克希思公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-107904216-A | It is engineered imine reduction enzyme and the method for ketone and the reduction amination of amine compounds | 科德克希思公司 | 2018-04-13 | — | — | CN | disclosed |
| CN-107699548-A | Hydroxylated biocatalyst and method for compound | 科德克希思公司 | 2018-02-16 | — | — | CN | disclosed |
| CN-104428313-B | Engineered imine reductases and methods for reductive amination of ketone and amine compounds | 科德克希思公司 | 2017-11-17 | — | — | CN | disclosed |
| CN-104428412-B | Biocatalysts and methods for hydroxylation of chemical compounds | 科德克希思公司 | 2017-09-08 | — | — | CN | disclosed |
| CN-107022020-A | The animal erythropoietin polypeptides and its purposes of modification | AMBRX公司 | 2017-08-08 | — | — | CN | disclosed |
| CN-107002050-A | Engineered imine reductases and methods for reductive amination of ketone and amine compounds | 科德克希思公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-104508126-B | Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs | 科德克希思公司 | 2017-06-30 | — | — | CN | disclosed |
| CN-103555782-B | Production of monatin and monatin precursors | 嘉吉有限公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-106443006-A | Methods and compositions comprising non-natural amino acids | AMBRX公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-105647824-A | In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris | 斯克利普斯研究院 | 2016-06-08 | — | — | CN | disclosed |