Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 17/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12070248 | 0.83 | GCK (0.60) | GCKMMP2MMP3MMP9MMP14 | |
| SCHEMBL3600059 | 0.81 | GCK (0.60) | GCK | |
| SCHEMBL9987196 | 0.80 | GCK (0.62) | GCKPTGS2 | |
| Formic Acid SCHEMBL28079833 | 0.80 | GCK (0.56) | GCKPTGS2 | |
| SCHEMBL1107736 | 0.80 | GCK (0.60) | GCKPTGS2 | |
| SCHEMBL10329791 | 0.80 | GCK (0.60) | GCK | |
| SCHEMBL2666561 | 0.78 | GCK (0.59) | GCK | |
| SCHEMBL1107599 | 0.77 | GCK (0.61) | GCK | |
| SCHEMBL9986825 | 0.77 | GCK (0.55) | GCK | |
| SCHEMBL9034923 | 0.77 | PTGS2 (0.55) | GCKPTGS2MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279283-A | Novel activators of glucokinase | 症变治疗公司 | 2017-01-04 | — | — | CN | disclosed |
| CN-101821276-B | Novel glucokinase activators | 症变治疗公司 | 2016-08-31 | — | — | CN | disclosed |