Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.94 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.94 |
| ▸ | MAOA | P21397 | 3/20 | 0.94 |
| ▸ | MAOB | P27338 | 2/20 | 0.94 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.94 |
| ▸ | ELANE | P08246 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aloe-Emodin SCHEMBL29814516 | 0.97 | MEN1 (1.00) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL309756 | 0.97 | MEN1 (1.00) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL29398579 | 0.97 | MEN1 (1.00) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL28756496 | 0.94 | MEN1 (0.89) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL8827767 | 0.94 | MEN1 (0.94) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL8929970 | 0.93 | MEN1 (0.86) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL5857045 | 0.93 | MEN1 (0.86) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL972434 | 0.89 | MEN1 (0.84) | MEN1KMT2AMAOAMAOBEPHX2 | |
| SCHEMBL13475629 | 0.88 | MEN1 (0.78) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL1195370 | 0.86 | MEN1 (0.80) | MEN1KMT2AMAOAMAOBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110286177-B | Method for detecting barbaloin | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | 2022-08-30 | — | — | CN | disclosed |
| CN-110286177-A | A method of detection barbaloin | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | 2019-09-27 | — | — | CN | disclosed |
| CN-105699567-B | Molecular imprinting nanometer magnetic bead dispersive solid-phase extraction is used for the detection method of giant knotweed metabolite group in rat plasma with mass spectrometry | 南京医科大学 | 2017-03-15 | — | — | CN | disclosed |
| CN-105699567-A | Method for detecting giant knot weed metabolic substance group in rat plasma through combination of molecular imprinting nanometer magnetic bead dispersive solid-phase extraction and mass spectrum | 南京医科大学 | 2016-06-22 | — | — | CN | disclosed |