Aloe-Emodin

Aloe-Emodin

SCHEMBL309756

O=C1c2cccc(O)c2C(=O)c2c(O)cc(CO)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
MAOA P21397 3/20 1.00
MAOB P27338 2/20 1.00
EPHX2 P34913 2/20 1.00
ALDH1A1 P00352 3/20 0.65
MAPT P10636 3/20 0.65
TSHR P16473 3/20 0.65
TDP1 Q9NUW8 3/20 0.65
MAPK1 P28482 2/20 0.65
LMNA P02545 2/20 0.65
HPGD P15428 2/20 0.65
ALOX15 P16050 2/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
HSD17B10 Q99714 2/20 0.65
HTT P42858 1/20 0.65
ELANE P08246 3/20 0.62
KDM4E B2RXH2 2/20 0.62
CYP3A4 P08684 2/20 0.62
RECQL P46063 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aloe-Emodin SCHEMBL29398579 1.00 MEN1 (1.00) MEN1KMT2AMAOAMAOBEPHX2
Aloe-Emodin SCHEMBL29814516 1.00 MEN1 (1.00) MEN1KMT2AMAOAMAOBEPHX2
Aloe-Emodin SCHEMBL28079854 0.97 MEN1 (0.94) MEN1KMT2AMAOAMAOBEPHX2
Aloe-Emodin SCHEMBL8827767 0.97 MEN1 (0.94) MEN1KMT2AMAOAMAOBEPHX2
Aloe-Emodin SCHEMBL28756496 0.94 MEN1 (0.89) MEN1KMT2AMAOAMAOBEPHX2
Aloe-Emodin SCHEMBL8929970 0.93 MEN1 (0.86) MEN1KMT2AMAOAMAOBEPHX2
Aloe-Emodin SCHEMBL5857045 0.93 MEN1 (0.86) MEN1KMT2AMAOAMAOBEPHX2
Aloe-Emodin SCHEMBL972434 0.92 MEN1 (0.84) MEN1KMT2AMAOAMAOBEPHX2
Aloe-Emodin SCHEMBL1195370 0.89 MEN1 (0.80) MEN1KMT2AMAOAMAOBEPHX2
Rhein SCHEMBL5017539 0.89 MEN1 (0.80) MEN1KMT2AMAOAMAOBEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5711 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122017224-A Method for screening antibacterial compounds by high-flux targeted phytophthora elicitin based on DHE fluorescence intensity and application 南京农业大学三亚研究院 2026-05-12 CN claimed
EP-4714440-A2 A HEALING HERBAL-MINERAL COMPOSITION WITH ENHANCED EFFECTS Kurek, Janusz (PL) 2026-03-25 EP claimed
CN-116577448-B Quality control method of magnolia bark and seven-material soup 华南农业大学 2026-02-27 CN claimed
EP-4684792-A1 ANTIMICROBIAL AGENT AND USE THEREOF Herzog, Artur (CH) 2026-01-28 EP claimed
EP-4108265-B1 FUNCTIONALIZED BIOLOGICAL MATRIX MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF VENUS MEDTECH HANGZHOU INC (CN) 2025-09-03 EP claimed
US-12403218-B2 Biological valve material, preparation method, and cross-linking agent CHINESE ACADEMY OF MEDICAL SCIENCES INSTITUTE OF BIOMEDICAL ENGINEERING (CN) 2025-09-02 US claimed
EP-3807287-B1 METAL COMPLEXES OF BETA-DIKETONES AND/OR POLYPHENOLS BY GREEN CHEMISTRY, PREPARATION METHOD THEREOF, SUNSCREEN THEREOF, SKIN OR HAIR TONE CONCEALER THEREOF, HAIR DYEING THEREOF AND OTHER USES THEREOF RAMIREZ RIOS LILIANA PATRICIA (NL) 2025-07-30 EP claimed
CN-120161158-A Method for measuring content of 12 components in supernatant tablet by high performance liquid chromatography 亳州市食品药品检验中心(亳州市药品和医疗器械不良反应(事件)监测中心) 2025-06-17 CN claimed
CN-120131600-A Use of aloe-emodin in treating or preventing acne 北京中医药大学 2025-06-13 CN claimed
CN-120082106-A Bacterial cellulose-aloe-emodin-vanillin composite membrane, preparation method and application 南开大学 2025-06-03 CN claimed
CN-1088907-A The preparation method of diacetyl rhein MADAUS AG (DE) 1994-07-06 CN claimed
EP-0525073-B1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA DU PONT (US) 1994-05-25 EP claimed
EP-0525073-A1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA. DU PONT (US) 1993-02-03 EP claimed
WO-1991015954-A1 ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-31 WO claimed
EP-0374890-A1 Process for the production of anthraquinone derivatives GERUM ESTABLISHMENT (LI) 1990-06-27 EP claimed
US-4670265-A TOPICAL APPLICATION UNIVERSITY OF MARYLAND, THE, A BODY CORP. OF MD 1987-06-02 US claimed
US-4602913-A Use of hydroxyanthraquinones for the coloration of human keratin fibres L'OREAL (FR) 1986-07-29 US claimed
US-4481185-A Stable emulsions obtained from a natural emulsifier stabilized with aloes juice SOCIETE ANONYME DITE: L'OREAL (FR) 1984-11-06 US claimed
EP-0046270-A1 Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them INTERx RESEARCH CORPORATION (US) 1982-02-24 EP claimed
US-4215062-A Anthracycline synthesis UNIVERSITY OF KANSAS ENDOWMENT ASSOCIATION (US) 1980-07-29 US claimed