Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.84 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.84 |
| ▸ | MAOA | P21397 | 3/20 | 0.84 |
| ▸ | MAOB | P27338 | 2/20 | 0.84 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aloe-Emodin SCHEMBL8827767 | 0.92 | MEN1 (0.94) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL309756 | 0.92 | MEN1 (1.00) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL29398579 | 0.92 | MEN1 (1.00) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL29814516 | 0.92 | MEN1 (1.00) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL28079854 | 0.89 | MEN1 (0.94) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL5857045 | 0.88 | MEN1 (0.86) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL8929970 | 0.88 | MEN1 (0.86) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL28756496 | 0.86 | MEN1 (0.89) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Aloe-Emodin SCHEMBL1195370 | 0.84 | MEN1 (0.80) | MEN1KMT2AMAOAMAOBEPHX2 | |
| Rhein SCHEMBL5017539 | 0.84 | MEN1 (0.80) | MEN1KMT2AMAOAMAOBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324411-B2 | Process for the preparation of DIACEREIN | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2012-12-04 | — | — | US | disclosed |
| US-20110015269-A1 | PROCESS FOR THE PREPARATION OF DIACERIN | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2011-01-20 | — | — | US | disclosed |
| EP-2234953-A1 | PROCESS FOR THE PREPARATION OF DIACERIN | Laboratorio Chimico Internazionale S.p.A. (IT) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009090483-A1 | PROCESS FOR THE PREPARATION OF DIACERIN | LABORATORIO CHIMICO INTERNAZIONALE S.P.A. (IT) | 2009-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015269-A1 | PROCESS FOR THE PREPARATION OF DIACERIN | ALOX15B, ALOX12, ACAT1 | MEN1 1265/4885KMT2A 3332/4885MAOA 630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.