Nitrobenzene

Nitrobenzene

SCHEMBL28079896

CCI.O=[N+]([O-])c1ccccc1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.73
LMNA P02545 2/20 0.73
L3MBTL1 Q9Y468 2/20 0.55
CRHBP P24387 2/20 0.55
CRHR2 Q13324 2/20 0.55
KMT2A Q03164 2/20 0.55
MEN1 O00255 1/20 0.55
ATM Q13315 1/20 0.55
TLR9 Q9NR96 1/20 0.55
TSHR P16473 2/20 0.50
HPGD P15428 1/20 0.50
ALOX12 P18054 1/20 0.50
CYP1A2 P05177 2/20 0.49
CYP2C19 P33261 2/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
MAPT P10636 2/20 0.48
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
ACHE P22303 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrobenzene SCHEMBL4658242 0.91 ALDH1A1 (0.80) ALDH1A1LMNAL3MBTL1CRHBPCRHR2
Nitrobenzene SCHEMBL7977386 0.86 ALDH1A1 (0.73) ALDH1A1LMNAL3MBTL1CRHBPCRHR2
Nitrobenzene SCHEMBL11740952 0.86 ALDH1A1 (0.73) ALDH1A1LMNAL3MBTL1CRHBPCRHR2
Nitrobenzene SCHEMBL27737077 0.86 ALDH1A1 (0.73) ALDH1A1LMNAL3MBTL1CRHBPCRHR2
Nitrobenzene SCHEMBL27684754 0.85 ALDH1A1 (0.89) ALDH1A1LMNAL3MBTL1CRHBPCRHR2
Nitrobenzene SCHEMBL20411 0.85
Nitrobenzene SCHEMBL2358164 0.85 ALDH1A1 (1.00) ALDH1A1LMNAL3MBTL1CRHBPCRHR2
Nitrobenzene SCHEMBL9669095 0.85
Nitrobenzene SCHEMBL15525745 0.85 ALDH1A1 (1.00) ALDH1A1LMNAL3MBTL1CRHBPCRHR2
Nitrobenzene SCHEMBL1330825 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105683155-A Novel diamine, polyamic acid, and polyimide 日产化学工业株式会社 2016-06-15 CN disclosed