Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.68 |
| ▸ | HTR2A | P28223 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL8589684 | 0.89 | MAOA (0.65) | MAOAHTR2ASMN1; SMN2HDAC3HDAC4 | |
| Benzene SCHEMBL28170833 | 0.89 | MAOA (0.85) | MAOAHTR2ASMN1; SMN2CYP2A6TAAR1 | |
| SCHEMBL52482 | 0.89 | MAOA (0.85) | MAOAHTR2ASMN1; SMN2CYP2A6TAAR1 | |
| Ammonia Solution, Strong SCHEMBL7296242 | 0.86 | MAOA (0.81) | MAOAHTR2ASMN1; SMN2CYP2A6TAAR1 | |
| Water SCHEMBL28661260 | 0.86 | MAOA (0.81) | MAOAHTR2ASMN1; SMN2CYP2A6TAAR1 | |
| SCHEMBL27510111 | 0.86 | MAOA (0.81) | MAOAHTR2ASMN1; SMN2CYP2A6TAAR1 | |
| Iodide SCHEMBL6672340 | 0.86 | MAOA (0.81) | MAOAHTR2ASMN1; SMN2CYP2A6TAAR1 | |
| Bromide SCHEMBL5311946 | 0.86 | MAOA (0.81) | MAOAHTR2ASMN1; SMN2CYP2A6TAAR1 | |
| Hydrochloric Acid SCHEMBL1551608 | 0.86 | MAOA (0.81) | MAOAHTR2ASMN1; SMN2CYP2A6TAAR1 | |
| Glutarate SCHEMBL4744748 | 0.86 | HDAC3 (0.74) | MAOAHTR2ASMN1; SMN2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120192295-A | Arylpropylamine derivative and application thereof | 江苏恩华药业股份有限公司 | 2025-06-24 | — | — | CN | disclosed |
| CN-105777706-A | 3-[(benzo[d][1,3]dioxolane-4-yl)-oxy]-3-arylpropylamine compound and application thereof | 江苏恩华药业股份有限公司 | 2016-07-20 | — | — | CN | disclosed |