Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.60 |
| ▸ | CTNNB1 | P35222 | 11/20 | 0.52 |
| ▸ | TCF7L2 | Q9NQB0 | 11/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856618 | 0.83 | CTNNB1 (0.46) | HTR2CCTNNB1TCF7L2SIGMAR1 | |
| SCHEMBL2882852 | 0.78 | HTR2C (0.61) | HTR2C | |
| SCHEMBL2856457 | 0.78 | PIK3CA (0.52) | HTR2C | |
| SCHEMBL2786916 | 0.77 | PIK3CA (0.51) | HTR2C | |
| SCHEMBL2805981 | 0.77 | HTR2C (0.98) | HTR2C | |
| SCHEMBL2807509 | 0.76 | SRC (0.54) | HTR2C | |
| SCHEMBL3755710 | 0.76 | HTR2C (1.00) | HTR2C | |
| SCHEMBL2807570 | 0.74 | PIK3CA (0.56) | HTR2C | |
| SCHEMBL13947563 | 0.73 | HTR2C (0.83) | HTR2C | |
| SCHEMBL2859459 | 0.73 | HTR2C (0.49) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |