Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CAMK1D | Q8IU85 | 2/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2786916 | 0.93 | PIK3CA (0.51) | HTR2CPIK3CAMAPK14ABL1SRC | |
| SCHEMBL2878746 | 0.90 | HTR2C (0.61) | HTR2CPIK3CAMAPK14GBA1 | |
| SCHEMBL2856457 | 0.85 | PIK3CA (0.52) | HTR2CPIK3CAMAPK14ABL1SRC | |
| SCHEMBL2807570 | 0.79 | PIK3CA (0.56) | HTR2CPIK3CAABL1SRCNPC1 | |
| SCHEMBL2882852 | 0.75 | HTR2C (0.61) | HTR2CPIK3CAABL1SRC | |
| SCHEMBL2788332 | 0.74 | PIK3CA (0.55) | HTR2CPIK3CAABL1SRCMAPT | |
| SCHEMBL2878573 | 0.74 | PIK3CA (0.62) | HTR2CPIK3CAMAPTLMNAMAPK1 | |
| SCHEMBL2808009 | 0.73 | HTR2C (0.60) | HTR2C | |
| SCHEMBL2807943 | 0.71 | SRC (0.68) | HTR2CPIK3CAABL1SRCUSP2 | |
| SCHEMBL2788589 | 0.71 | SRC (0.68) | HTR2CPIK3CAABL1SRCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |