Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.56 |
| ▸ | SRC | P12931 | 10/20 | 0.54 |
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | ABL1 | P00519 | 7/20 | 0.49 |
| ▸ | CCR4 | P51679 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2807943 | 0.88 | SRC (0.68) | PIK3CASRCHTR2CABL1RAB9A | |
| SCHEMBL2856457 | 0.84 | PIK3CA (0.52) | PIK3CASRCHTR2CABL1NPC1 | |
| SCHEMBL2788332 | 0.83 | PIK3CA (0.55) | PIK3CASRCHTR2CABL1 | |
| SCHEMBL2786916 | 0.83 | PIK3CA (0.51) | PIK3CASRCHTR2CABL1NPC1 | |
| SCHEMBL2859459 | 0.79 | HTR2C (0.49) | PIK3CASRCHTR2CABL1NPC1 | |
| SCHEMBL2882852 | 0.78 | HTR2C (0.61) | PIK3CASRCHTR2CABL1 | |
| SCHEMBL2861201 | 0.78 | PIK3CA (0.46) | PIK3CASRCHTR2CABL1 | |
| SCHEMBL2788589 | 0.76 | SRC (0.68) | PIK3CASRCHTR2CABL1 | |
| SCHEMBL2857759 | 0.76 | ALDH1A1 (0.44) | PIK3CASRCHTR2CABL1 | |
| SCHEMBL2786942 | 0.76 | HRH4 (0.54) | SRCHTR2CABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |