Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Chlorobenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.85 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.43 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.43 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.43 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL28109636 | 0.92 | TSHR (0.85) | TSHRCYP1A2CYP2A6LMNACES2 | |
| Chlorobenzene SCHEMBL9350340 | 0.92 | — | — | |
| Chlorobenzene SCHEMBL28793798 | 0.92 | TSHR (0.85) | TSHRCYP1A2CYP2A6LMNACES2 | |
| Chlorobenzene SCHEMBL1962905 | 0.92 | TSHR (0.85) | TSHRCYP1A2CYP2A6LMNACES2 | |
| Chlorobenzene SCHEMBL7445312 | 0.92 | TSHR (0.85) | TSHRCYP1A2CYP2A6LMNACES2 | |
| SCHEMBL24715429 | 0.92 | TSHR (1.00) | TSHRCYP1A2CYP2A6LMNACES2 | |
| Chlorobenzene SCHEMBL1330702 | 0.92 | — | — | |
| Chlorobenzene SCHEMBL1568605 | 0.92 | TSHR (1.00) | TSHRCYP1A2CYP2A6LMNACES2 | |
| Chlorobenzene SCHEMBL2168046 | 0.92 | TSHR (1.00) | TSHRCYP1A2CYP2A6LMNACES2 | |
| Chlorobenzene SCHEMBL2044 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114907634-A | Flame-retardant reinforced modified plastic particle and preparation method thereof | 界首市亚鑫塑业科技有限公司 | 2022-08-16 | — | — | CN | claimed |
| CN-111718235-B | Method for recovering Jiale musk chlorobenzene solvent | 安徽金轩科技有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-111732118-B | Method for treating galaxolide musk waste aluminum salt water | 安徽金轩科技有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-114085124-A | Industrial impurity removal method for prophase waste liquid of Jiale musk chlorobenzene | 安徽金轩科技有限公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-111848336-A | Method for treating galaxolide musk waste aluminum water | 安徽金轩科技有限公司 | 2020-10-30 | — | — | CN | disclosed |
| CN-111807940-A | Method for recycling waste methanol in galaxolide production | 安徽金轩科技有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-111807924-A | Method for recycling galaxolide waste liquid | 安徽金轩科技有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-111732118-A | Method for treating galaxolide musk waste aluminum salt water | 安徽金轩科技有限公司 | 2020-10-02 | — | — | CN | disclosed |
| CN-111718235-A | Method for recovering Jiale musk chlorobenzene solvent | 安徽金轩科技有限公司 | 2020-09-29 | — | — | CN | disclosed |
| CN-110563671-A | Preparation method of photoinitiator 2-methyl-1- (4-methylthiophenyl) -2-morpholinyl-1-acetone | 宁夏沃凯珑新材料有限公司 | 2019-12-13 | — | — | CN | disclosed |
| CN-105777525-A | Separating and purifying method for 2-(4-ethyl benzene formyl) benzoic acid | 北京恒石尚德科技有限公司 | 2016-07-20 | — | — | CN | disclosed |