SCHEMBL28080391

SCHEMBL28080391

CCOC(=O)c1cc(C)cnc1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.49
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
TSHR P16473 1/20 0.44
ALDH1A1 P00352 4/20 0.44
GLA P06280 2/20 0.44
GAA P10253 2/20 0.44
HPGD P15428 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
MAPT P10636 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
LMNA P02545 1/20 0.43
MAPK1 P28482 1/20 0.43
ATM Q13315 1/20 0.43
NPC1 O15118 1/20 0.42
TP53 P04637 1/20 0.42
RAB9A P51151 1/20 0.42
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29859779 0.90 TSHR (0.47) KDM4ECYP2C9CYP2C19TSHRALDH1A1
SCHEMBL6559030 0.90 TSHR (0.47) KDM4ECYP2C9CYP2C19TSHRALDH1A1
SCHEMBL28080390 0.89 ALDH1A1 (0.46) KDM4ECYP2C9CYP2C19TSHRALDH1A1
SCHEMBL31261177 0.87 TSHR (0.44) KDM4ETSHRALDH1A1GLAGAA
SCHEMBL23500733 0.87 CYP2C9 (0.47) KDM4ECYP2C9CYP2C19TSHRALDH1A1
SCHEMBL28983538 0.86 KDM4E (0.48) KDM4ECYP2C9CYP2C19TSHRALDH1A1
SCHEMBL31261191 0.84 TSHR (0.42) KDM4ETSHRALDH1A1GLAGAA
SCHEMBL28080388 0.83 ATM (0.46) KDM4ETSHRALDH1A1GLAMAPT
SCHEMBL28603823 0.82 CYP4F2 (0.52) KDM4ECYP2C9CYP2C19TSHRALDH1A1
SCHEMBL612735 0.81 KDM4E (0.51) KDM4ETSHRALDH1A1GLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113061125-A Preparation method of imidazolidinone compound 沈阳中化农药化工研发有限公司 2021-07-02 CN disclosed
CN-109384714-B Process for recovering and process for producing substituted or unsubstituted 2, 3-pyridinedicarboxylic acid 北京颖泰嘉和生物科技股份有限公司 2021-04-30 CN disclosed
CN-105777623-A Method for preparing pyridine side chain methyl quaternary ammonium compound 北京颖泰嘉和生物科技股份有限公司 2016-07-20 CN disclosed