Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | SMPD2 | O60906 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 2/20 | 0.43 |
| ▸ | CHAT | P28329 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL7228806 | 0.90 | TDP1 (0.46) | MTNR1AMTNR1BHDAC8HDAC6MEN1 | |
| Naphthalene SCHEMBL28160129 | 0.88 | MTNR1A (0.50) | MTNR1AMTNR1BHDAC8HDAC6MEN1 | |
| SCHEMBL35849993 | 0.88 | MEN1 (0.57) | MTNR1AMTNR1BHDAC8HDAC6MEN1 | |
| SCHEMBL9005 | 0.88 | MEN1 (0.57) | MTNR1AMTNR1BHDAC8HDAC6MEN1 | |
| SCHEMBL3115624 | 0.86 | MEN1 (0.55) | MTNR1AMTNR1BHDAC8HDAC6MEN1 | |
| Potassium SCHEMBL31317026 | 0.86 | MEN1 (0.55) | MTNR1AMTNR1BHDAC8HDAC6MEN1 | |
| SCHEMBL31323327 | 0.86 | MEN1 (0.55) | MTNR1AMTNR1BHDAC8HDAC6MEN1 | |
| SCHEMBL3109583 | 0.86 | MEN1 (0.55) | MTNR1AMTNR1BHDAC8HDAC6MEN1 | |
| SCHEMBL11132298 | 0.86 | MEN1 (0.55) | MTNR1AMTNR1BHDAC8HDAC6MEN1 | |
| Hydrochloric Acid SCHEMBL10384676 | 0.86 | MEN1 (0.55) | MTNR1AMTNR1BHDAC8HDAC6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105802608-A | Preparation method of fluorescent probe and application of fluorescent probe in aluminum ion detection | 温州医科大学 | 2016-07-27 | — | — | CN | claimed |
| CN-113448171-B | Photosensitive resin composition, pattern forming method, and method for producing substrate protective coating film | 赫拉化学科技有限公司 | 2024-04-16 | — | — | CN | disclosed |