Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CHAT | P28329 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | SMPD2 | O60906 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28080393 | 0.90 | MTNR1A (0.47) | TDP1MEN1LMNATHRBBLM | |
| SCHEMBL35849993 | 0.89 | MEN1 (0.57) | TDP1MEN1LMNATHRBBLM | |
| SCHEMBL9005 | 0.89 | MEN1 (0.57) | TDP1MEN1LMNATHRBBLM | |
| SCHEMBL11132298 | 0.87 | MEN1 (0.55) | TDP1MEN1LMNATHRBBLM | |
| Hydrochloric Acid SCHEMBL31671086 | 0.87 | MEN1 (0.55) | TDP1MEN1LMNATHRBBLM | |
| SCHEMBL3107253 | 0.87 | MEN1 (0.55) | TDP1MEN1LMNATHRBBLM | |
| Potassium SCHEMBL31317026 | 0.87 | MEN1 (0.55) | TDP1MEN1LMNATHRBBLM | |
| Hydrochloric Acid SCHEMBL10384676 | 0.87 | MEN1 (0.55) | TDP1MEN1LMNATHRBBLM | |
| SCHEMBL3109583 | 0.87 | MEN1 (0.55) | TDP1MEN1LMNATHRBBLM | |
| SCHEMBL3115624 | 0.87 | MEN1 (0.55) | TDP1MEN1LMNATHRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |